Madhurima Singh, Ph.D.

2011 Biological Sciences University of South Carolina, Columbia, SC 
General Biology, Molecular Biology, Cell Biology
"Madhurima Singh"
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Rekha C. Patel grad student 2011 University of South Carolina
 (Regulation of PKR activation by PACT and TRBP in response to stress signals.)
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Singh M, Patel RC. (2012) Increased interaction between PACT molecules in response to stress signals is required for PKR activation. Journal of Cellular Biochemistry. 113: 2754-64
Singh M, Castillo D, Patel CV, et al. (2011) Stress-induced phosphorylation of PACT reduces its interaction with TRBP and leads to PKR activation. Biochemistry. 50: 4550-60
Singh M, Fowlkes V, Handy I, et al. (2009) Essential role of PACT-mediated PKR activation in tunicamycin-induced apoptosis. Journal of Molecular Biology. 385: 457-68
Daher A, Laraki G, Singh M, et al. (2009) TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress. Molecular and Cellular Biology. 29: 254-65
Saxena S, Singh M, Engisch K, et al. (2005) Rab proteins regulate epithelial sodium channel activity in colonic epithelial HT-29 cells Biochemical and Biophysical Research Communications. 337: 1219-1223
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