Michael DeRan, Ph.D.

2011 University of Rochester, Rochester, NY 
Biochemistry, Cell Biology, Genetics
"Michael DeRan"
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Jiyong Zhao grad student 2011 Rochester
 (The Role of NPAT in S-Phase-Dependent Histone Gene Transcription and DNA Double-Strand Break Repair.)
Xu Wu post-doc MGH/Harvard
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He L, Jhong JH, Chen Q, et al. (2021) Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors. Cell Reports. 37: 109955
Shalhout SZ, Yang PY, Grzelak EM, et al. (2021) YAP-dependent proliferation by a small molecule targeting annexin A2. Nature Chemical Biology
Li Q, Sun Y, Jarugumilli GK, et al. (2020) Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell
Eelen G, Dubois C, Cantelmo AR, et al. (2018) Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature
Jarugumilli GK, Choi JR, Chan P, et al. (2018) Chemical probe to identify the cellular targets of the reactive lipid metabolite 2-trans-hexadecenal. Acs Chemical Biology
Chen B, Zheng B, DeRan M, et al. (2016) ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity. Nature Chemical Biology
Chan P, Han X, Zheng B, et al. (2016) Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway. Nature Chemical Biology
DeRan M, Yang J, Shen CH, et al. (2014) Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein. Cell Reports. 9: 495-503
Chen EY, DeRan MT, Ignatius MS, et al. (2014) Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 111: 5349-54
Chen E, DeRan M, Grandinetti KB, et al. (2014) Abstract A14: Canonical WNT/β-catenin pathway activation suppresses embryonal rhabdomyosarcoma growth and self-renewal Molecular Cancer Research. 12
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