Richard Chien, Ph.D.
Affiliations: | 2010 | Biomedical Sciences - Ph.D. | University of California, Irvine, Irvine, CA |
Area:
Biochemistry, Molecular BiologyGoogle:
"Richard Chien"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Kyoko Yokomori | grad student | 2010 | UC Irvine | |
| (Examination of Cohesin's role in mammalian gene regulation.) | ||||
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Publications
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| Newkirk DA, Chen YY, Chien R, et al. (2017) The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome. Clinical Epigenetics. 9: 89 |
| Hu CM, Zhu J, Guo XE, et al. (2015) Novel small molecules disrupting Hec1/Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism. Oncogene. 34: 1220-30 |
| Chien R, Zeng W, Ball AR, et al. (2011) Cohesin: a critical chromatin organizer in mammalian gene regulation. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 89: 445-58 |
| Chien R, Zeng W, Kawauchi S, et al. (2011) Cohesin mediates chromatin interactions that regulate mammalian β-globin expression. The Journal of Biological Chemistry. 286: 17870-8 |
| Zeng W, de Greef JC, Chen YY, et al. (2009) Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD). Plos Genetics. 5: e1000559 |