Luke L. Lairson

Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
"Luke Lairson"
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Brittney Beyer research assistant Calibr
Chelsea Green research assistant Scripps Research Institute
Katharine Moore research assistant Scripps Institute
Tom Vokes research assistant Calibr
Justin Anglin post-doc Calibr
Reza Beheshti Zavareh post-doc Calibr (Physics Tree)
Emily Chin post-doc Calibr
Ching Ding post-doc Calibr
Natasha C. Lucki post-doc Calibr (Cell Biology Tree)
Warren Plaisted post-doc Calibr
Benjamin Sadrian post-doc Calibr (Neurotree)
Naja Vergani post-doc Calibr
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Huffman BJ, Chen S, Schwarz JL, et al. (2020) Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonists. Nature Chemistry
Marro BS, Zak J, Zavareh RB, et al. (2019) Discovery of Small Molecules for the Reversal of T Cell Exhaustion. Cell Reports. 29: 3293-3302.e3
Lucki NC, Villa GR, Vergani N, et al. (2019) A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America
Holt MC, Assar Z, Beheshti Zavareh R, et al. (2018) Biochemical Characterization and Structure-based Mutational Analysis Provides Insight into Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry
Bollong MJ, Lee G, Coukos JS, et al. (2018) A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature
Anglin J, Zavareh RB, Sander PN, et al. (2018) Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma. Bioorganic & Medicinal Chemistry Letters
Beyer BA, Fang M, Sadrian B, et al. (2017) Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation. Nature Chemical Biology
Bollong MJ, Pietilä M, Pearson AD, et al. (2017) A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers. Proceedings of the National Academy of Sciences of the United States of America
Lum KM, Sato Y, Beyer BA, et al. (2017) Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. Acs Chemical Biology
Huan T, Forsberg EM, Rinehart D, et al. (2017) Systems biology guided by XCMS Online metabolomics. Nature Methods. 14: 461-462
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