Doug Young

College of William and Mary, Williamsburg, VA 
"Doug Young"
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Rust HL, Subramanian V, West GM, et al. (2014) Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. Acs Chemical Biology. 9: 649-55
Govan JM, Young DD, Lusic H, et al. (2013) Optochemical control of RNA interference in mammalian cells. Nucleic Acids Research. 41: 10518-28
Young DD, Jockush S, Turro NJ, et al. (2011) Synthetase polyspecificity as a tool to modulate protein function. Bioorganic & Medicinal Chemistry Letters. 21: 7502-4
Minnihan EC, Young DD, Schultz PG, et al. (2011) Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase. Journal of the American Chemical Society. 133: 15942-5
Young TS, Young DD, Ahmad I, et al. (2011) Evolution of cyclic peptide protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 11052-6
Dush MK, McIver AL, Parr MA, et al. (2011) Heterotaxin: a TGF-β signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos. Chemistry & Biology. 18: 252-63
Young DD, Young TS, Jahnz M, et al. (2011) An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity. Biochemistry. 50: 1894-900
Karginov AV, Zou Y, Shirvanyants D, et al. (2011) Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. Journal of the American Chemical Society. 133: 420-3
Young DD, Connelly CM, Grohmann C, et al. (2010) Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. Journal of the American Chemical Society. 132: 7976-81
Young DD, Lively MO, Deiters A. (2010) Activation and deactivation of DNAzyme and antisense function with light for the photochemical regulation of gene expression in mammalian cells. Journal of the American Chemical Society. 132: 6183-93
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