Stephen R. Sprang, Ph.D.

Affiliations: 
Biological Science University of Montana, Missoula, MT 
Area:
Structural Biology and Biochemistry: Biological Signal Transduction
Website:
http://www.cas.umt.edu/casweb/faculty/FacultyDetails.cfm?id=941
Google:
"Stephen Sprang"
Bio:

http://www.hhmi.com/research/investigators/sprang_bio.html

Mean distance: 8.11
 
SNBCP

Parents

Sign in to add mentor
Muttaiya (Sunda) Sundaralingam grad student 1977 UW Madison
 (Structural and conformational studies of purine nucleoside analogs)
Robert J. Fletterick post-doc 1983 UCSF
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

McClelland LJ, Zhang K, Mou TC, et al. (2020) Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1. Nature Communications. 11: 1077
Zeng B, Mou TC, Doukov TI, et al. (2019) Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A. Structure (London, England : 1993)
Maziarz M, Leyme A, Marivin A, et al. (2018) Atypical activation of Gαq by the oncogenic mutation Q209P. The Journal of Biological Chemistry
Kant R, Zeng B, Thomas CJ, et al. (2016) Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα. Elife. 5
Black LA, Thomas CJ, Nix GN, et al. (2016) Nanosecond Dynamics of Gαi1 Bound to Nucleotides or Ric-8A, a Gα Chaperone with GEF Activity. Biophysical Journal. 111: 722-31
Kant R, Zeng B, Thomas CJ, et al. (2016) Author response: Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα Elife
Hahn DK, Tusell JR, Sprang SR, et al. (2015) Catalytic Mechanism of Mammalian Adenylyl Cyclase: A Computational Investigation. Biochemistry. 54: 6252-62
Van Eps N, Thomas CJ, Hubbell WL, et al. (2015) The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1. Proceedings of the National Academy of Sciences of the United States of America. 112: 1404-9
McClelland LJ, Mou TC, Jeakins-Cooley ME, et al. (2014) Structure of a mitochondrial cytochrome c conformer competent for peroxidase activity. Proceedings of the National Academy of Sciences of the United States of America. 111: 6648-53
Sprang SR. (2013) An acid test for g proteins. Molecular Cell. 51: 405-6
See more...