Stephen R. Sprang, Ph.D.
Affiliations: | Biological Science | University of Montana, Missoula, MT |
Area:
Structural Biology and Biochemistry: Biological Signal TransductionWebsite:
http://www.cas.umt.edu/casweb/faculty/FacultyDetails.cfm?id=941Google:
"Stephen Sprang"Bio:
http://www.hhmi.com/research/investigators/sprang_bio.html
Mean distance: 8.11 | S | N | B | C | P |
Parents
Sign in to add mentorMuttaiya (Sunda) Sundaralingam | grad student | 1977 | UW Madison | |
(Structural and conformational studies of purine nucleoside analogs) | ||||
Robert J. Fletterick | post-doc | 1983 | UCSF |
Children
Sign in to add traineeMichael J. Eck | grad student | 1987-1991 | University of Texas Southwestern Medical School |
R Bryan Sutton | grad student | 1992-1997 | UT Southwestern |
Tsan Sam Xiao | grad student | 1995-2000 | University of Texas Southwester Medical Center |
James H. Naismith | post-doc | 1993-1994 | University of Texas Southwestern Medical Center at Dallas |
John J. Tesmer | post-doc | 1996-1999 | UT Southwestern (Cell Biology Tree) |
Tsan Sam Xiao | post-doc | 2000-2001 | University of Texas Southwester Medical Center |
BETA: Related publications
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Publications
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McClelland LJ, Zhang K, Mou TC, et al. (2020) Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1. Nature Communications. 11: 1077 |
McClelland LJ, Zhang K, Mou T, et al. (2020) Ric8A-Gα, a Complex Structure of a Guanine Nucleotide Exchange Factor Biophysical Journal. 118: 335a |
Zeng B, Mou TC, Doukov TI, et al. (2019) Structure, Function, and Dynamics of the Gα Binding Domain of Ric-8A. Structure (London, England : 1993) |
Sprang S, McClelland L, Johnston J, et al. (2019) The structure of the complex of the cytoplasmic guanine nucleotide exchange factor Ric-8A bound to Gαi1 Acta Crystallographica Section a Foundations and Advances. 75: a175-a175 |
Maziarz M, Leyme A, Marivin A, et al. (2018) Atypical activation of Gαq by the oncogenic mutation Q209P. The Journal of Biological Chemistry |
Stump S, Mou TC, Sprang SR, et al. (2018) Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene. Plos One. 13: e0205584 |
Sprang S, Zeng B, McClelland L, et al. (2017) Structures of Ric-8A, a G protein chaperone and activator Acta Crystallographica Section a Foundations and Advances. 73: a367-a367 |
Black LA, Ross J, Sprang SR. (2017) Nucleotide and Nucleotide Exchange Factor Bound Nano to Millisecond Structural-Dynamics of G Alpha Biophysical Journal. 112: 281a |
Kant R, Zeng B, Thomas CJ, et al. (2016) Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα. Elife. 5 |
McClelland LJ, Steele HB, Whitby FG, et al. (2016) Cytochrome c Can Form a Well-Defined Binding Pocket for Hydrocarbons. Journal of the American Chemical Society |