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Steven E. Ealick

Affiliations:

Chemistry and Chemical Biology

Cornell University, Ithaca, NY, United States

Area:

structure and function of proteins using X-ray crystallography

Website:

http://chemistry.cornell.edu/faculty/detail.cfm?netid=see3

Google:

"Steven E. Ealick"

Bio:

http://bmcb.cornell.edu/faculty/ealick.html

Mean distance: 12.14

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Parents

Dick van der Helm	grad student	1976	University of Oklahoma
(The crystal and molecular structures of eupalmerin acetate, eupalmerin acetate dibromide, a dimer ketone, a trimer diketone and four non-planar spirodilactams)

Children

Chenglong Li	grad student	2000	Cornell
Todd C. Appleby	grad student	2001	Cornell
Eric M. Bennett	grad student	2003	Cornell
Ruchi Anand	grad student	2004	Cornell
Jacob A. Bauer	grad student	2004	Cornell
Ethan C. Settembre	grad student	2004	Cornell
Erika V. Soriano	grad student	2007	Cornell
Christopher T. Jurgenson	grad student	2008	Cornell
Shridhar Bale	grad student	2009	Cornell
Mariya Morar	grad student	2009	Cornell
Jarrod B. French	grad student	2010	Cornell
Kathryn M. McCulloch	grad student	2010	Cornell
Debamita Paul	grad student	2010	Cornell
Megan C. Kopp	grad student	2014	Cornell

Collaborators

collaborator

BETA: Related publications

Publications

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Fenwick MK, Su D, Dong M, et al. (2020) Structural basis of substrate selectivity of viperin. Biochemistry
Parker WB, Allan PW, Waud WR, et al. (2020) The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors. Cancer Chemotherapy and Pharmacology
Fenwick MK, Dong M, Lin H, et al. (2019) Crystal structure of Dph2 in complex with elongation factor 2 reveals structural basis for first step of diphthamide biosynthesis. Biochemistry
Mahanta N, Hicks KA, Naseem S, et al. (2019) Menaquinone Biosynthesis: Biochemical and Structural Studies on chorismate dehydratase. Biochemistry
Fenwick MK, Ealick SE. (2018) Towards the structural characterization of the human methyltransferome. Current Opinion in Structural Biology. 53: 12-21
Dong M, Kathiresan V, Fenwick MK, et al. (2018) Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science (New York, N.Y.). 359: 1247-1250
Fenwick MK, Almabruk KH, Ealick SE, et al. (2017) Biochemical characterization and structural basis of reactivity and regioselectivity differences of Burkholderia thailandensis and Burkholderia glumae 1,6-didesmethyltoxoflavin N-methyltransferase. Biochemistry
Fenwick MK, Li Y, Cresswell P, et al. (2017) Structural studies of viperin, an antiviral radical SAM enzyme. Proceedings of the National Academy of Sciences of the United States of America
Dong M, Horitani M, Dzikovski B, et al. (2017) Substrate-Dependent Cleavage Site Selection by Unconventional Radical SAM Enzymes in Diphthamide Biosynthesis. Journal of the American Chemical Society
Rodrigues MJ, Windeisen V, Zhang Y, et al. (2017) Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis. Nature Chemical Biology

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