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Frederick Alt, PhD

Affiliations: 
Immunology Harvard University, Cambridge, MA, United States 
Area:
DNA repair, immunology, lymphoma
Website:
http://www.childrenshospital.org/cfapps/research/data_admin/Site143/mainpageS143P0.html
Google:
"Frederick Alt"
Bio:

http://searchworks.stanford.edu/view/761131

Mean distance: 14.7 (cluster 31)
 		SNBCP
Cross-listing: Neurotree - Cell Biology Tree

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Parents

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Robert T. Schimke grad student 1977 Stanford
 (The molecular mechanism of dihydrofolate reductase overproduction in methotrexate-resistant variants of culture murine cells)
David Baltimore post-doc 1982 MIT

Children

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George Yancopoulos grad student Columbia University Medical School (Neurotree)
Darryll D. Dudley grad student 2003 Harvard (Neurotree)
Sean E. Rooney grad student 2003 Harvard (Neurotree)
David H. Jung grad student 2006 Harvard (Neurotree)
Cristian Boboila grad student 2005-2011 Harvard (Neurotree)
Tingting Zhang-Kharas grad student 2005-2011 Harvard
Suprawee Tepsuporn grad student 2013 Harvard (Neurotree)
Uttiya Basu post-doc Harvard (Neurotree)
Huan Chen post-doc Harvard (Cell Biology Tree)
Bjoern Schwer post-doc (Neurotree)
Ronald A. DePinho post-doc 1984-1988 Columbia
Angela K. Eggleston post-doc 1999-1999 Harvard Medical School - Boston Children's Hospital
Shan Zha post-doc 2004-2009 Harvard - Boston Children's Hospital
Richard L Frock post-doc 2010-2017 Harvard Medical School - Boston Children's Hospital (Cell Biology Tree)

Collaborators

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Publications

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Ratnaparkhe M, Wong JKL, Wei PC, et al. (2018) Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors. Nature Communications. 9: 4760
Chang AN, Liang Z, Dai HQ, et al. (2018) Neural blastocyst complementation enables mouse forebrain organogenesis. Nature
Lin SG, Ba Z, Alt FW, et al. (2018) RAG Chromatin Scanning During V(D)J Recombination and Chromatin Loop Extrusion are Related Processes. Advances in Immunology. 139: 93-135
Layer JV, Cleary JP, Brown AJ, et al. (2018) Parp3 promotes long-range end joining in murine cells. Proceedings of the National Academy of Sciences of the United States of America
Alt FW, Schwer B. (2018) DNA double-strand breaks as drivers of neural genomic change, function, and disease. Dna Repair
Tian M, Alt FW. (2018) Guiding a mutator in antibody diversification. Cell Research
Duan H, Chen X, Boyington JC, et al. (2018) Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies. Immunity
Crowe JL, Shao Z, Wang XS, et al. (2018) Kinase-dependent structural role of DNA-PKcs during immunoglobulin class switch recombination. Proceedings of the National Academy of Sciences of the United States of America
Ru H, Mi W, Zhang P, et al. (2018) DNA melting initiates the RAG catalytic pathway. Nature Structural & Molecular Biology
Jain S, Ba Z, Zhang Y, et al. (2018) CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning. Cell
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