Frederick W. Alt, PhD
Affiliations: | Genetics | Harvard University, Cambridge, MA, United States |
Area:
DNA repair, immunology, lymphomaWebsite:
https://www.hms.harvard.edu/dms/bbs/fac/Alt.phpGoogle:
"Frederick W. Alt"Bio:
https://genetics.hms.harvard.edu/faculty-staff/frederick-w-alt
https://www.hhmi.org/scientists/frederick-w-alt
http://searchworks.stanford.edu/view/761131
Mean distance: 14.7 (cluster 31) | S | N | B | C | P |
Cross-listing: Neurotree - Cell Biology Tree
Parents
Sign in to add mentor| Robert T. Schimke | grad student | 1977 | Stanford | |
| (The molecular mechanism of dihydrofolate reductase overproduction in methotrexate-resistant variants of culture murine cells) | ||||
| David Baltimore | post-doc | 1982 | MIT | |
Children
Sign in to add trainee| George Yancopoulos | grad student | Columbia University Medical School (Neurotree) | |
| Yang Xu | grad student | 1994 | Harvard (Stem Cell Tree) |
| Darryll D. Dudley | grad student | 2003 | Harvard (Neurotree) |
| Sean E. Rooney | grad student | 2003 | Harvard (Neurotree) |
| David H. Jung | grad student | 2006 | Harvard (Neurotree) |
| Cristian Boboila | grad student | 2005-2011 | Harvard (Neurotree) |
| Tingting Zhang-Kharas | grad student | 2005-2011 | Harvard |
| Suprawee Tepsuporn | grad student | 2013 | Harvard (Neurotree) |
| Uttiya Basu | post-doc | Harvard (Neurotree) | |
| Huan Chen | post-doc | Harvard (Cell Biology Tree) | |
| Bjoern Schwer | post-doc | (Neurotree) | |
| Adam Yongxin Ye | post-doc | 2018- | Harvard Medical School (GenetiTree) |
| Ronald A. DePinho | post-doc | 1984-1988 | Columbia |
| Angela K. Eggleston | post-doc | 1999-1999 | Harvard Medical School - Boston Children's Hospital |
| Shan Zha | post-doc | 2004-2009 | Harvard - Boston Children's Hospital |
| Richard L Frock | post-doc | 2010-2017 | Harvard Medical School - Boston Children's Hospital (Cell Biology Tree) |
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Publications
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| Tian M, Cheng HL, Kimble MT, et al. (2021) An in vivo method for diversifying the functions of therapeutic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Chen X, Zhou T, Schmidt SD, et al. (2021) Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity |
| Dai HQ, Hu H, Lou J, et al. (2021) Loop extrusion mediates physiological Igh locus contraction for RAG scanning. Nature |
| Zhang X, Yoon HS, Chapdelaine-Williams AM, et al. (2021) Physiological role of the 3'IgH CBEs super-anchor in antibody class switching. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Dai HQ, Liang Z, Chang AN, et al. (2020) Direct analysis of brain phenotypes via neural blastocyst complementation. Nature Protocols |
| Ba Z, Lou J, Ye AY, et al. (2020) CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning. Nature |
| Chen H, Zhang Y, Ye AY, et al. (2020) BCR selection and affinity maturation in Peyer's patch germinal centres. Nature |
| Tena A, Zhang Y, Kyritsis N, et al. (2020) Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture. Proceedings of the National Academy of Sciences of the United States of America |
| Tian M, McGovern K, Cheng HL, et al. (2020) Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. Proceedings of the National Academy of Sciences of the United States of America |
| Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948 |