Frederick W. Alt, PhD

Affiliations: 
Genetics Harvard University, Cambridge, MA, United States 
Area:
DNA repair, immunology, lymphoma
Website:
https://www.hms.harvard.edu/dms/bbs/fac/Alt.php
Google:
"Frederick W. Alt"
Bio:

https://genetics.hms.harvard.edu/faculty-staff/frederick-w-alt
https://www.hhmi.org/scientists/frederick-w-alt
http://searchworks.stanford.edu/view/761131

Mean distance: 14.7 (cluster 31)
 
SNBCP
Cross-listing: Neurotree - Cell Biology Tree

Parents

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Robert T. Schimke grad student 1977 Stanford
 (The molecular mechanism of dihydrofolate reductase overproduction in methotrexate-resistant variants of culture murine cells)
David Baltimore post-doc 1982 MIT

Children

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George Yancopoulos grad student Columbia University Medical School (Neurotree)
Yang Xu grad student 1994 Harvard (Stem Cell Tree)
Darryll D. Dudley grad student 2003 Harvard (Neurotree)
Sean E. Rooney grad student 2003 Harvard (Neurotree)
David H. Jung grad student 2006 Harvard (Neurotree)
Cristian Boboila grad student 2005-2011 Harvard (Neurotree)
Tingting Zhang-Kharas grad student 2005-2011 Harvard
Suprawee Tepsuporn grad student 2013 Harvard (Neurotree)
Uttiya Basu post-doc Harvard (Neurotree)
Huan Chen post-doc Harvard (Cell Biology Tree)
Bjoern Schwer post-doc (Neurotree)
Adam Yongxin Ye post-doc 2018- Harvard Medical School (GenetiTree)
Ronald A. DePinho post-doc 1984-1988 Columbia
Angela K. Eggleston post-doc 1999-1999 Harvard Medical School - Boston Children's Hospital
Shan Zha post-doc 2004-2009 Harvard - Boston Children's Hospital
Richard L Frock post-doc 2010-2017 Harvard Medical School - Boston Children's Hospital (Cell Biology Tree)
BETA: Related publications

Publications

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Tian M, Cheng HL, Kimble MT, et al. (2021) An in vivo method for diversifying the functions of therapeutic antibodies. Proceedings of the National Academy of Sciences of the United States of America. 118
Chen X, Zhou T, Schmidt SD, et al. (2021) Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity
Dai HQ, Hu H, Lou J, et al. (2021) Loop extrusion mediates physiological Igh locus contraction for RAG scanning. Nature
Zhang X, Yoon HS, Chapdelaine-Williams AM, et al. (2021) Physiological role of the 3'IgH CBEs super-anchor in antibody class switching. Proceedings of the National Academy of Sciences of the United States of America. 118
Dai HQ, Liang Z, Chang AN, et al. (2020) Direct analysis of brain phenotypes via neural blastocyst complementation. Nature Protocols
Ba Z, Lou J, Ye AY, et al. (2020) CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning. Nature
Chen H, Zhang Y, Ye AY, et al. (2020) BCR selection and affinity maturation in Peyer's patch germinal centres. Nature
Tena A, Zhang Y, Kyritsis N, et al. (2020) Induction of recurrent break cluster genes in neural progenitor cells differentiated from embryonic stem cells in culture. Proceedings of the National Academy of Sciences of the United States of America
Tian M, McGovern K, Cheng HL, et al. (2020) Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. Proceedings of the National Academy of Sciences of the United States of America
Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948
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