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Hening Lin

Chemistry and Chemical Biology Cornell University, Ithaca, NY, United States 
chemistry, biology, and application of enzymes
"Hening Lin"

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Virginia W. Cornish grad student 2003 Columbia
 (Development and application of chemical complementation: A high -throughput assay for enzyme evolution and proteomics.)
Christopher T. Walsh post-doc 2003-2006 Harvard Medical School


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Brian Wang research assistant 2011-2013 Cornell
Xuling Zhu grad student 2011 Cornell
Xiaoyang Su grad student 2013 Cornell
Xiaoyu Zhang grad student 2012-2017 Cornell
Sadhan Jana post-doc Cornell
Ying-Ling Chiang post-doc 2013-2016
Cheng-Liang Zhu post-doc 2018-2019 Cornell
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Zhang Y, Su D, Dzikovski B, et al. (2021) Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe-4S] to a [4Fe-4S] Cluster in Dph1-Dph2. Journal of the American Chemical Society
Hong JY, Fernandez I, Anmangandla A, et al. (2021) Pharmacological Advantage of SIRT2-Selective versus pan-SIRT1-3 Inhibitors. Acs Chemical Biology
Wang M, Lin H. (2021) Understanding the Function of Mammalian Sirtuins and Protein Lysine Acylation. Annual Review of Biochemistry
Abril YLN, Fernandez IR, Hong JY, et al. (2021) Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer. Oncogene
Hong JY, Jing H, Price IR, et al. (2020) Simultaneous Inhibition of SIRT2 Deacetylase and Defatty-Acylase Activities via a PROTAC Strategy. Acs Medicinal Chemistry Letters. 11: 2305-2311
Son SI, Su D, Ho TT, et al. (2020) Garcinol Is an HDAC11 Inhibitor. Acs Chemical Biology
Zhang M, Zhou L, Xu Y, et al. (2020) A STAT3 palmitoylation cycle promotes T17 differentiation and colitis. Nature
Bi D, Yang J, Hong JY, et al. (2020) Substrate-Dependent Modulation of SIRT2 by a Fluorescent Probe, 1-Aminoanthracene. Biochemistry
Kosciuk T, Lin H. (2020) NMT as a glycine and lysine myristoyltransferase in cancer, immunity, and infections. Acs Chemical Biology
Kosciuk T, Price IR, Zhang X, et al. (2020) NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle. Nature Communications. 11: 1067
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