Manohar Ratnam

College of Medicine The University of Toledo 
Molecular Biology, Biochemistry, Oncology
"Manohar Ratnam"
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Soave C, Ducker C, Kim S, et al. (2022) Identification of ELK1 interacting peptide segments in the androgen receptor. The Biochemical Journal
Rosati R, Oppat K, Huang Y, et al. (2020) Clinical association of progesterone receptor isoform A with breast cancer metastasis consistent with its unique mechanistic role in preclinical models. Bmc Cancer. 20: 512
Pardy L, Rosati R, Soave C, et al. (2019) The ternary complex factor protein ELK1 is an independent prognosticator of disease recurrence in prostate cancer. The Prostate
Patki M, McFall T, Rosati R, et al. (2018) Chronic p27 Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor. Scientific Reports. 8: 16006
Rosati R, Polin LA, Ducker C, et al. (2018) Strategy for Tumor Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Frontera ED, Khansa RM, Schalk DL, et al. (2018) IgA Fc-folate conjugate activates and recruits neutrophils to directly target triple-negative breast cancer cells. Breast Cancer Research and Treatment
Rosati R, Patki M, Chari V, et al. (2016) The Amino-terminal Domain of the Androgen Receptor Co-opts ERK Docking Sites in ELK1 to Induce Sustained Gene Activation that Supports Prostate Cancer Cell Growth. The Journal of Biological Chemistry
Rosati R, Chen B, Patki M, et al. (2016) Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease HSP90 and the Androgen Receptor Levels and Inhibit Viability in Enzalutamide Resistant C4-2 Prostate Cancer Cells. Molecular Pharmacology
Patki M, Huang Y, Ratnam M. (2016) Restoration of the cellular secretory milieu overrides androgen dependence of in vivo generated castration resistant prostate cancer cells overexpressing the androgen receptor. Biochemical and Biophysical Research Communications
McFall T, Patki M, Rosati R, et al. (2015) Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges. Oncotarget. 6: 33146-64
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