Jean Bidlack

School of Medicine and Dentistry University of Rochester, Rochester, NY 
Biochemistry, Molecular Biology, Cell Biology
"Jean Bidlack"
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Lefever M, Li Y, Anglin B, et al. (2015) Structural Requirements for CNS Active Opioid Glycopeptides. Journal of Medicinal Chemistry. 58: 5728-41
Li Y, St Louis L, Knapp BI, et al. (2014) Can amphipathic helices influence the CNS antinociceptive activity of glycopeptides related to β-endorphin? Journal of Medicinal Chemistry. 57: 2237-46
Sromek AW, Provencher BA, Russell S, et al. (2014) Preliminary pharmacological evaluation of enantiomeric morphinans. Acs Chemical Neuroscience. 5: 93-9
Provencher BA, Sromek AW, Li W, et al. (2013) Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors. Journal of Medicinal Chemistry. 56: 8872-8
VanAlstine MA, Wentland MP, Alvarez J, et al. (2013) Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. Bioorganic & Medicinal Chemistry Letters. 23: 2128-33
Hoot MR, Sypek EI, Reilley KJ, et al. (2013) Inhibition of Gβγ-subunit signaling potentiates morphine-induced antinociception but not respiratory depression, constipation, locomotion, and reward. Behavioural Pharmacology. 24: 144-52
Wentland MP, Jo S, Gargano JM, et al. (2012) Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 8. High affinity ligands for opioid receptors in the picomolar Ki range: oxygenated N-(2-[1,1'-biphenyl]-4-ylethyl) analogues of 8-CAC. Bioorganic & Medicinal Chemistry Letters. 22: 7340-4
Neumeyer JL, Zhang B, Zhang T, et al. (2012) Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors. Journal of Medicinal Chemistry. 55: 3878-90
Li Y, Lefever MR, Muthu D, et al. (2012) Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins. Future Medicinal Chemistry. 4: 205-26
Dean RL, Eyerman D, Todtenkopf MS, et al. (2012) Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats. Pharmacology, Biochemistry, and Behavior. 100: 530-7
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