Suzanne G. Rzuczek, Ph.D.
Affiliations: | 2011 | Graduate School - New Brunswick | Rutgers University, New Brunswick, New Brunswick, NJ, United States |
Area:
Pharmacy, Organic ChemistryGoogle:
"Suzanne Rzuczek"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Joseph E. Rice | grad student | 2011 | Rutgers, New Brunswick | |
| (Design and Synthesis of G-Quadruplex Selective Macrocyclic Polyoxazoles.) | ||||
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Publications
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| Wang ZF, Ursu A, Childs-Disney JL, et al. (2018) The Hairpin Form of r(GC) in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small Molecules. Cell Chemical Biology |
| Angelbello AJ, González ÀL, Rzuczek SG, et al. (2016) Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1. Bioorganic & Medicinal Chemistry Letters |
| Tran T, Childs-Disney JL, Liu B, et al. (2014) Targeting the r(CGG) repeats that cause FXTAS with modularly assembled small molecules and oligonucleotides. Acs Chemical Biology. 9: 904-12 |
| Blankson G, Rzuczek SG, Bishop C, et al. (2013) Macrocyclic pyridyl polyoxazoles: structure-activity studies of the aminoalkyl side-chain on G-quadruplex stabilization and cytotoxic activity. Molecules (Basel, Switzerland). 18: 11938-63 |
| Satyanarayana M, Kim YA, Rzuczek SG, et al. (2010) Macrocyclic hexaoxazoles: Influence of aminoalkyl substituents on RNA and DNA G-quadruplex stabilization and cytotoxicity. Bioorganic & Medicinal Chemistry Letters. 20: 3150-4 |
| Rzuczek SG, Pilch DS, Liu A, et al. (2010) Macrocyclic pyridyl polyoxazoles: selective RNA and DNA G-quadruplex ligands as antitumor agents. Journal of Medicinal Chemistry. 53: 3632-44 |
| Tsai YC, Qi H, Lin CP, et al. (2009) A G-quadruplex stabilizer induces M-phase cell cycle arrest. The Journal of Biological Chemistry. 284: 22535-43 |
| Satyanarayana M, Rzuczek SG, Lavoie EJ, et al. (2008) Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency. Bioorganic & Medicinal Chemistry Letters. 18: 3802-4 |
| Pilch DS, Barbieri CM, Rzuczek SG, et al. (2008) Targeting human telomeric G-quadruplex DNA with oxazole-containing macrocyclic compounds. Biochimie. 90: 1233-49 |
| Rzuczek SG, Pilch DS, LaVoie EJ, et al. (2008) Lysinyl macrocyclic hexaoxazoles: synthesis and selective G-quadruplex stabilizing properties. Bioorganic & Medicinal Chemistry Letters. 18: 913-7 |