Mesfin Gonit, Ph.D.

Affiliations: 
2011 College of Medicine The University of Toledo 
Area:
Molecular Biology, Biochemistry, Oncology
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"Mesfin Gonit"
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Manohar Ratnam grad student 2011 The University of Toledo
 (The Androgen Receptor as a Transcriptional Co-activator: Implications in the Growth and Progression of Prostate Cancer.)
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Publications

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Patki M, Chari V, Sivakumaran S, et al. (2013) The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells Journal of Biological Chemistry. 288: 11047-11065
Ratnam M, Patki M, Gonit M, et al. (2013) Mechanisms of ARE-independent gene activation by the androgen receptor in prostate cancer cells: Potential targets for better intervention strategies Androgen-Responsive Genes in Prostate Cancer: Regulation, Function and Clinical Applications. 2147483647: 85-100
Gonit M, Zhang J, d'Alincourt Salazar M, et al. (2011) Hormone depletion-insensitivity of prostate cancer cells is supported by the AR without binding to classical response elements Molecular Endocrinology. 25: 621-634
Sivakumaran S, Zhang J, Kelley KM, et al. (2010) Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα. The Journal of Steroid Biochemistry and Molecular Biology. 122: 333-40
Zhang J, Gonit M, Salazar MD, et al. (2010) C/EBPα redirects androgen receptor signaling through a unique bimodal interaction Oncogene. 29: 723-738
Elnakat H, Gonit M, Salazar MDA, et al. (2009) Regulation of folate receptor internalization by protein kinase C Biochemistry. 48: 8249-8260
Zhang J, Wilkinson JE, Gonit M, et al. (2008) Expression and sub-cellular localization of the CCAAT/enhancer binding protein α in relation to postnatal development and malignancy of the prostate Prostate. 68: 1206-1214
Lu Y, Wu J, Wu J, et al. (2007) Role of formulation composition in folate receptor-targeted liposomal doxorubicin delivery to acute myelogenous leukemia cells. Molecular Pharmaceutics. 4: 707-12
Blaser BW, Gonit M, Qi H, et al. (2007) Induction of folate receptor type β in a bone marrow engraftment model of acute myelogenous leukemia [22] Leukemia. 21: 2233-2235
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