Prashanth T. Bhaskar, Ph.D.
Affiliations: | 2008 | University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States |
Area:
Molecular Biology, Cell BiologyGoogle:
"Prashanth Bhaskar"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Nissim Hay | grad student | 2008 | University of Illinois at Chicago, Health Sciences Center | |
| (Role of the Tsc2-mTOR pathway in apoptosis.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Blaha CS, Ramakrishnan G, Jeon SM, et al. (2022) A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis. Nature Communications. 13: 899 |
| Yu WN, Nogueira V, Sobhakumari A, et al. (2015) Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration. Cell Reports. 12: 610-21 |
| Patra KC, Wang Q, Bhaskar PT, et al. (2013) Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer. Cancer Cell. 24: 213-28 |
| Patra K, Wang Q, Bhaskar P, et al. (2013) Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer Cancer Cell. 24: 399 |
| Chen CC, Jeon SM, Bhaskar PT, et al. (2010) FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor. Developmental Cell. 18: 592-604 |
| Bhaskar PT, Nogueira V, Patra KC, et al. (2009) mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition. Molecular and Cellular Biology. 29: 5136-47 |
| Bhaskar PT, Hay N. (2007) The two TORCs and Akt. Developmental Cell. 12: 487-502 |
| Skeen JE, Bhaskar PT, Chen CC, et al. (2006) Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. Cancer Cell. 10: 269-80 |
| Majewski N, Nogueira V, Bhaskar P, et al. (2004) Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Molecular Cell. 16: 819-30 |