Polina V. Shcherbakova
Affiliations: | Cancer Research | University of Nebraska Medical Center, Omaha, NE, United States |
Area:
Biochemistry, GeneticsGoogle:
"Polina Shcherbakova"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Matthew R. Northam | grad student | 2012 | University of Nebraska Medical Center |
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Publications
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| Ostroverkhova D, Tyryshkin K, Beach AK, et al. (2024) DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors. Cell Reports. 43: 113655 |
| Barbari SR, Beach AK, Markgren JG, et al. (2022) Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ variants at low dNTP levels. Nucleic Acids Research |
| Stepchenkova EI, Zhuk AS, Cui J, et al. (2021) Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28. Genetics |
| Bulock CR, Xing X, Shcherbakova PV. (2020) Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant. Nucleic Acids Research |
| Lee M, Eng G, Barbari SR, et al. (2020) Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorectal and Endometrial Tumors. Clinical and Translational Gastroenterology. 11: e00149 |
| Bulock CR, Xing X, Shcherbakova PV. (2020) DNA polymerase δ proofreads errors made by DNA polymerase ε. Proceedings of the National Academy of Sciences of the United States of America |
| Parkash V, Kulkarni Y, Ter Beek J, et al. (2019) Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε. Nature Communications. 10: 373 |
| Xing X, Kane DP, Bulock CR, et al. (2019) A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme. Nature Communications. 10: 374 |
| Barbari SR, Kane DP, Moore EA, et al. (2018) Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae. G3 (Bethesda, Md.) |
| Barbari SR, Shcherbakova PV. (2017) Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy. Dna Repair |