Carol A. Fierke, Ph. D.

Affiliations: 
Chemistry, Biological chemsitry University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Enzymology, metalloenzymes, ribozyme, RNA
Website:
http://www.lsa.umich.edu/chem/people/faculty/fierkecarol_ci
Google:
"Carol A. Fierke"
Bio:

http://www.umich.edu/~caflab/caf.htm
http://www.nano.med.umich.edu/Members/Fierke.html

Mean distance: 7.51
 
SNBCP
Cross-listing: MichiganTree

Parents

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William P. Jencks grad student 1984 Brandeis
 (Utilization of CoA binding energy for catalysis and effect of salts and buffers on a proton transfer reaction from fumarase to solvent)
Stephen J. Benkovic post-doc Penn State

Children

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Jane E. Jackman grad student 1999 Duke
Sharon McGee Crary grad student 1993-1999 Duke
Jeffrey C. Kurz grad student 2001 Duke
Jennifer S. Pickett grad student 2003 University of Michigan
Laura Michele Rozan grad student 2003 University of Michigan (Neurotree)
Jeremy J. Day grad student 2004 University of Michigan
Heather L. Hartman grad student 2005 University of Michigan
Katherine A. Hicks grad student 2005 University of Michigan
Nissa M. Westerberg grad student 2005 University of Michigan
Andrew J. Andrews grad student 2006 University of Michigan
Stephanie L. Gantt grad student 2006 University of Michigan
Manoj Cheriyan grad student 2007 University of Michigan
Rebekah A. Kelly grad student 2007 University of Michigan
June E. Pais grad student 2007 University of Michigan
Jean K. Smith-Koutmos grad student 2009 University of Michigan
Anette Casiano-Negroni grad student 2010 University of Michigan
Samuel G. Gattis grad student 2010 University of Michigan
Tamiika K. Hurst grad student 2010 University of Michigan
Xiaomu Guan grad student 2011 University of Michigan
Wan H. Lim grad student 2011 University of Michigan
Caleb G. Joseph grad student 2012 University of Michigan
Corissa L. Lamphear grad student 2012 University of Michigan
Da Wang grad student 2012 University of Michigan
Xin Liu grad student 2007-2013 University of Michigan
Yu Chen grad student 2010-2015 University of Michigan
Bradley P. Klemm grad student 2012-2017 University of Michigan
Jeffrey E. Lopez grad student 2012-2017 University of Michigan
Matthew Saderholm post-doc 1998-1999 Duke University School of Medicine
James L. Hougland post-doc 2005-2010 University of Michigan
BETA: Related publications

Publications

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Karasik A, Wilhelm CA, Fierke CA, et al. (2020) Disease-associated mutations in mitochondrial precursor tRNAs affect binding, m1R9 methylation and tRNA processing by mtRNase P. Rna (New York, N.Y.)
Liu W, Yang K, Ma X, et al. (2020) A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors. Chemmedchem
Henley MJ, Linhares BM, Morgan BS, et al. (2020) Unexpected specificity within dynamic transcriptional protein-protein complexes. Proceedings of the National Academy of Sciences of the United States of America
Yang KS, Ma XR, Ma Y, et al. (2020) A Speedy Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors. Biorxiv : the Preprint Server For Biology
Teramoto T, Kaitany KJ, Kakuta Y, et al. (2020) Pentatricopeptide repeats of protein-only RNase P use a distinct mode to recognize conserved bases and structural elements of pre-tRNA. Nucleic Acids Research
Sahoo BR, Bekier ME, Liu Z, et al. (2019) Structural Interaction of Apolipoprotein A-I Mimetic Peptide with Amyloid-β Generates Toxic Hetero-oligomers. Journal of Molecular Biology
Welker Leng K, Castaneda CA, Decroos C, et al. (2019) Phosphorylation of Histone Deacetylase 8: Structural and Mechanistic Analysis of Phosphomimetic S39E Mutant. Biochemistry
Karasik A, Fierke CA, Koutmos M. (2019) Interplay between substrate recognition, 5' end tRNA processing and methylation activity of human mitochondrial RNase P. Rna (New York, N.Y.)
Nissim S, Leshchiner I, Mancias JD, et al. (2019) Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nature Genetics
García-Torres D, Fierke CA. (2019) The chaperone SmgGDS-607 has a dual role, both activating and inhibiting farnesylation of small GTPases. The Journal of Biological Chemistry
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