Herman O. Sintim, DPhil

Chemistry and Biochemistry University of Maryland, College Park, College Park, MD 
Chemical Biology, Organic
"Herman O. Sintim"

PhD with David M. Hodgson (Oxford) in Organic Chemistry
Postdoc with Timothy Donohoe (Oxford) in Organic Chemistry
Postdoc with Eric Kool (Stanford) in Chemical Biology

Mean distance: 7.89


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David M. Hodgson grad student 2002 Oxford
Timothy J. Donohoe post-doc 2002-2004 Oxford
Eric T. Kool post-doc 2004-2006 Stanford


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Christopher R. Vickery research assistant
Modi Wang post-doc 2017- Purdue (BME Tree)
Dimpy Kalia post-doc 2012-2013 University of Maryland
Clinton Gregory Mikek post-doc 2017-2018 Purdue
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Onyedibe KI, Mohallem R, Wang M, et al. (2023) Proteomic and phosphoproteomic analyses of Jurkat T-cell treated with 2'3' cGAMP reveals various signaling axes impacted by cyclic dinucleotides. Journal of Proteomics. 279: 104869
Wang M, Chaudhuri R, Ong WWS, et al. (2021) c-di-GMP Induces COX-2 Expression in Macrophages in a STING-Independent Manner. Acs Chemical Biology
Dayal N, Wang M, Sintim HO. (2020) HSD1787, a Tetrahydro-3-Pyrazolo[4,3-]Quinoline Compound Synthesized via Povarov Reaction, Potently Inhibits Proliferation of Cancer Cell Lines at Nanomolar Concentrations. Acs Omega. 5: 23799-23807
Aryal UK, Hedrick V, Onyedibe KI, et al. (2020) Global Proteomic Analyses of STING-Positive and -Negative Macrophages Reveal STING and Non-STING Differentially Regulated Cellular and Molecular Pathways. Proteomics. Clinical Applications. e1900109
Huff K, Sintim H, Lescun T, et al. (2020) Effect of Novel Molecules Against Inflammation in Lipopolysaccharide (LPS)‐Stimulated Fibroblast‐Like Synoviocytes (FLS) The Faseb Journal. 34: 1-1
Sintim HO, Mikek CG, Wang M, et al. (2019) Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules. Medchemcomm. 10: 1999-2023
Onyedibe KI, Wang M, Sintim HO. (2019) ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1. Molecules (Basel, Switzerland). 24
Dayal N, Opoku-Temeng C, Mohammad H, et al. (2019) Inhibitors of Intracellular Gram-positive Bacteria Growth Synthesized via Povarov-Doebner Reactions. Acs Infectious Diseases
Dayal N, Mikek CG, Hernandez D, et al. (2019) Potently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors. European Journal of Medicinal Chemistry. 180: 449-456
Sintim HO, Al Mamari HH, Almohseni HAA, et al. (2019) Alkylation of lithiated dimethyl tartrate acetonide with unactivated alkyl halides and application to an asymmetric synthesis of the 2,8-dioxabicyclo[3.2.1]octane core of squalestatins/zaragozic acids. Beilstein Journal of Organic Chemistry. 15: 1194-1202
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