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Brian M. Weist, Ph.D.

Affiliations: 
2012 Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Immunology, Biochemistry, Molecular Biology, Cell Biology
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Craig M. Walsh grad student 2012 UC Irvine
 (The role of Drak2 in T cell mediated alloresponses.)

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Kurd NS, Hoover A, Yoon J, et al. (2020) Factors that influence the thymic selection of CD8αα intraepithelial lymphocytes. Mucosal Immunology
Weist BM, Kurd N, Boussier J, et al. (2015) Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition. Nature Immunology. 16: 635-41
Clarke EV, Weist BM, Walsh CM, et al. (2015) Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation. Journal of Leukocyte Biology. 97: 147-60
Yang KM, Kim W, Bae E, et al. (2012) DRAK2 participates in a negative feedback loop to control TGF-β/Smads signaling by binding to type I TGF-β receptor. Cell Reports. 2: 1286-99
Weinger JG, Weist BM, Plaisted WC, et al. (2012) MHC mismatch results in neural progenitor cell rejection following spinal cord transplantation in a model of viral-induced demyelination. Stem Cells (Dayton, Ohio). 30: 2584-95
Weist BM, Hernandez JB, Walsh CM. (2012) Loss of DRAK2 signaling enhances allogeneic transplant survival by limiting effector and memory T cell responses. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12: 2220-7
Lu JV, Weist BM, van Raam BJ, et al. (2011) Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proceedings of the National Academy of Sciences of the United States of America. 108: 15312-7
Bell BD, Leverrier S, Weist BM, et al. (2008) FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 16677-82
Arechiga AF, Bell BD, Leverrier S, et al. (2007) A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. Journal of Immunology (Baltimore, Md. : 1950). 179: 5291-300
Friedrich ML, Cui M, Hernandez JB, et al. (2007) Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes. The Journal of Biological Chemistry. 282: 4573-84
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