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Anna K. Mapp, Ph.D.

Affiliations: 
Chemistry, Medicinal Chemsitry University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Chemical biology
Website:
https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=amapp
Google:
"Anna Mapp"
Bio:

http://www.umich.edu/~mapplab/members/current-members/prof-anna-k-mapp.html

Mean distance: 7.36
 
SNBCP
Cross-listing: MichiganTree

Parents

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Clayton H. Heathcock grad student 1997 UC Berkeley
 (The total synthesis of myxalamide A)
Peter B. Dervan post-doc 1997-2000 Caltech
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Publications

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Pattelli ON, Valdivia EM, Beyersdorf MS, et al. (2024) A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts Med25 Protein-Protein Interactions. Angewandte Chemie (International Ed. in English). e202400781
Liu Y, Joy ST, Henley MJ, et al. (2023) Inhibition of CREB Binding and Function with a Dual-Targeting Ligand. Biochemistry
Breen ME, Joy ST, Baruti OJ, et al. (2023) Garcinolic acid distinguishes between GACKIX domains and modulates interaction networks. Chembiochem : a European Journal of Chemical Biology. e202300439
Pattelli ON, Valdivia EM, Beyersdorf MS, et al. (2023) A lipopeptidomimetic of transcriptional activation domains selectively disrupts Med25 PPIs. Biorxiv : the Preprint Server For Biology
Peiffer AL, Garlick JM, Joy ST, et al. (2022) Allostery in the dynamic coactivator domain KIX occurs through minor conformational micro-states. Plos Computational Biology. 18: e1009977
Joy ST, Henley MJ, De Salle SN, et al. (2021) A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb. Journal of the American Chemical Society
Garlick JM, Sturlis SM, Bruno PA, et al. (2021) Norstictic Acid Is a Selective Allosteric Transcriptional Regulator. Journal of the American Chemical Society
Henley MJ, Linhares BM, Morgan BS, et al. (2020) Unexpected specificity within dynamic transcriptional protein-protein complexes. Proceedings of the National Academy of Sciences of the United States of America
Annand JR, Henderson AR, Cole KS, et al. (2020) Gibberellin JRA-003: A Selective Inhibitor of Nuclear Translocation of IKKα. Acs Medicinal Chemistry Letters. 11: 1913-1918
Huang H, Howard CA, Zari S, et al. (2020) Covalent inhibition of NSD1 histone methyltransferase. Nature Chemical Biology
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