Scott Allen Armstrong
Affiliations: | Biology, Molecular and Cellular | Harvard University, Cambridge, MA, United States |
Area:
General Biology, Molecular Biology, Biochemistry, OncologyWebsite:
https://hsci.harvard.edu/people/scott-armstrong-md-phdGoogle:
"Scott Allen Armstrong"Bio:
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Parents
Sign in to add mentor| Michael Stuart Brown | grad student | 1994 | UT Southwestern | |
| (Molecular and biochemical characterization of Rab geranylgeranyl transferase.) | ||||
| Joseph L. Goldstein | grad student | 1994 | UT Southwestern | |
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Publications
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| Issa GC, Aldoss I, DiPersio J, et al. (2023) The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia. Nature |
| Uckelmann HJ, Haarer EL, Takeda R, et al. (2022) Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia. Cancer Discovery |
| Aubrey BJ, Cutler JA, Bourgeois W, et al. (2022) IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nature Cancer |
| Heikamp EB, Henrich JA, Perner F, et al. (2021) The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. Blood |
| Perner F, Schnoeder TM, Xiong Y, et al. (2021) YBX1 mediates translation of oncogenic transcripts to control cell competition in AML. Leukemia |
| Cai SF, Chu SH, Goldberg AD, et al. (2020) Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition. Cancer Discovery |
| Dzama MM, Steiner M, Rausch J, et al. (2020) Synergistic Targeting of FLT3 Mutations in AML via Combined Menin-MLL and FLT3 Inhibition. Blood |
| Perner F, Gadrey JY, Xiong Y, et al. (2020) Novel Inhibitors of the Histone-Methyltransferase DOT1L Show Potent Antileukemic Activity in Patient-derived Xenografts. Blood |
| Uckelmann HJ, Armstrong SA. (2020) Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention. Stem Cell Reports |
| Olsen SN, Armstrong SA. (2020) It's Not What You Say But How You Say It: Targeting RNA Methylation in AML. Molecular Cell. 78: 996-998 |