Scott Allen Armstrong

Biology, Molecular and Cellular Harvard University, Cambridge, MA, United States 
General Biology, Molecular Biology, Biochemistry, Oncology
"Scott Allen Armstrong"

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Michael Stuart Brown grad student 1994 UT Southwestern
 (Molecular and biochemical characterization of Rab geranylgeranyl transferase.)
Joseph L. Goldstein grad student 1994 UT Southwestern
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Issa GC, Aldoss I, DiPersio J, et al. (2023) The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia. Nature
Uckelmann HJ, Haarer EL, Takeda R, et al. (2022) Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia. Cancer Discovery
Aubrey BJ, Cutler JA, Bourgeois W, et al. (2022) IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nature Cancer
Heikamp EB, Henrich JA, Perner F, et al. (2021) The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. Blood
Perner F, Schnoeder TM, Xiong Y, et al. (2021) YBX1 mediates translation of oncogenic transcripts to control cell competition in AML. Leukemia
Cai SF, Chu SH, Goldberg AD, et al. (2020) Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition. Cancer Discovery
Dzama MM, Steiner M, Rausch J, et al. (2020) Synergistic Targeting of FLT3 Mutations in AML via Combined Menin-MLL and FLT3 Inhibition. Blood
Perner F, Gadrey JY, Xiong Y, et al. (2020) Novel Inhibitors of the Histone-Methyltransferase DOT1L Show Potent Antileukemic Activity in Patient-derived Xenografts. Blood
Uckelmann HJ, Armstrong SA. (2020) Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention. Stem Cell Reports
Olsen SN, Armstrong SA. (2020) It's Not What You Say But How You Say It: Targeting RNA Methylation in AML. Molecular Cell. 78: 996-998
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