Georg T. Wondrak

Affiliations: 
Pharmaceutical Sciences University of Arizona, Tucson, AZ 
Area:
Pharmacy, Biochemistry, Pharmacology, Oncology
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"Georg Wondrak"
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Publications

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de Faria Lopes L, Jandova J, Justiniano R, et al. (2022) The Glycolysis-Derived α-Dicarbonyl Metabolite Methylglyoxal is a UVA-Photosensitizer Causing the Photooxidative Elimination of Hacat Keratinocytes with Induction of Oxidative and Proteotoxic Stress Response Gene Expression. Photochemistry and Photobiology
Jandova J, Park SL, Corenblum MJ, et al. (2022) Mefloquine induces ER stress and apoptosis in BRAFi-resistant A375-BRAF /NRAS malignant melanoma cells targeting intracranial tumors in a bioluminescent murine model. Molecular Carcinogenesis
Jandova J, Snell J, Hua A, et al. (2021) Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin. Redox Biology. 45: 102042
Jandova J, Hua AB, Fimbres J, et al. (2021) Deuterium Oxide (DO) Induces Early Stress Response Gene Expression and Impairs Growth and Metastasis of Experimental Malignant Melanoma. Cancers. 13
Schmidlin CJ, Rojo de la Vega M, Perer J, et al. (2020) Activation of NRF2 by topical apocarotenoid treatment mitigates radiation-induced dermatitis. Redox Biology. 37: 101714
Justiniano R, de Faria Lopes L, Perer J, et al. (2020) The Endogenous Tryptophan-derived Photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) Is a Nanomolar Photosensitizer That Can Be Harnessed for the Photodynamic Elimination of Skin Cancer Cells in Vitro and in Vivo. Photochemistry and Photobiology
Perer J, Jandova J, Fimbres J, et al. (2020) The sunless tanning agent dihydroxyacetone induces stress response gene expression and signaling in cultured human keratinocytes and reconstructed epidermis. Redox Biology. 36: 101594
Jandova J, Perer J, Hua A, et al. (2020) Genetic Target Modulation Employing CRISPR/Cas9 Identifies Glyoxalase 1 as a Novel Molecular Determinant of Invasion and Metastasis in A375 Human Malignant Melanoma Cells In Vitro and In Vivo. Cancers. 12
Jandova J, Hua A, Dickinson SE, et al. (2020) 641 The cutaneous response to solar UV radiation is attenuated by chlorination stress originating from swimming pool disinfectants Journal of Investigative Dermatology. 140
Perer J, Jandova J, Fimbres J, et al. (2020) 609 The topical tanning agent dihydroxyacetone induces stress response gene expression and signaling in human reconstructed epidermis and SKH1 hairless mouse skin Journal of Investigative Dermatology. 140
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