Angela Wilks

Affiliations: 
Pharmaceutical Sciences University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Biochemistry, Molecular Biology, Cell Biology
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"Angela Wilks"
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Publications

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Heinzl GA, Huang W, Yu W, et al. (2016) Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa. Journal of Medicinal Chemistry
Smith AD, Modi AR, Sun S, et al. (2015) Spectroscopic Determination of Distinct Heme Ligands in Outer-Membrane Receptors PhuR and HasR of Pseudomonas aeruginosa. Biochemistry. 54: 2601-12
Smith AD, Wilks A. (2015) Differential contributions of the outer membrane receptors PhuR and HasR to heme acquisition in Pseudomonas aeruginosa. The Journal of Biological Chemistry. 290: 7756-66
Reinhart AA, Powell DA, Nguyen AT, et al. (2015) The prrF-encoded small regulatory RNAs are required for iron homeostasis and virulence of Pseudomonas aeruginosa. Infection and Immunity. 83: 863-75
Wilks A, Ikeda-Saito M. (2014) Heme utilization by pathogenic bacteria: not all pathways lead to biliverdin. Accounts of Chemical Research. 47: 2291-8
Nguyen AT, O'Neill MJ, Watts AM, et al. (2014) Adaptation of iron homeostasis pathways by a Pseudomonas aeruginosa pyoverdine mutant in the cystic fibrosis lung. Journal of Bacteriology. 196: 2265-76
Tripathi S, O'Neill MJ, Wilks A, et al. (2013) Crystal structure of the Pseudomonas aeruginosa cytoplasmic heme binding protein, Apo-PhuS. Journal of Inorganic Biochemistry. 128: 131-6
O'Neill MJ, Wilks A. (2013) The P. aeruginosa heme binding protein PhuS is a heme oxygenase titratable regulator of heme uptake. Acs Chemical Biology. 8: 1794-802
Hom K, Heinzl GA, Eakanunkul S, et al. (2013) Small molecule antivirulents targeting the iron-regulated heme oxygenase (HemO) of P. aeruginosa. Journal of Medicinal Chemistry. 56: 2097-109
Barker KD, Barkovits K, Wilks A. (2012) Metabolic flux of extracellular heme uptake in Pseudomonas aeruginosa is driven by the iron-regulated heme oxygenase (HemO). The Journal of Biological Chemistry. 287: 18342-50
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