Brooke M. Emerling, Ph.D.

Affiliations: 
2007 Northwestern University, Evanston, IL 
Area:
Molecular Biology, Cell Biology
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"Brooke Emerling"
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Navdeep S. Chandel grad student 2007 Northwestern
 (Signaling pathways regulating HIF-1.)
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Publications

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Yapindi L, Bowley T, Kurtaneck N, et al. (2023) Activation of p53-regulated pro-survival signals and hypoxia-independent mitochondrial targeting of TIGAR by human papillomavirus E6 oncoproteins. Virology. 585: 1-20
Emerling BM, Benes CH, Poulogiannis G, et al. (2013) Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients. Proceedings of the National Academy of Sciences of the United States of America. 110: 3483-8
Bell EL, Emerling BM, Ricoult SJ, et al. (2011) SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene. 30: 2986-96
Emerling BM, Weinberg F, Snyder C, et al. (2009) Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radical Biology & Medicine. 46: 1386-91
Emerling BM, Weinberg F, Liu JL, et al. (2008) PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proceedings of the National Academy of Sciences of the United States of America. 105: 2622-7
Emerling BM, Viollet B, Tormos KV, et al. (2007) Compound C inhibits hypoxic activation of HIF-1 independent of AMPK. Febs Letters. 581: 5727-31
Bell EL, Emerling BM, Chandel NS. (2005) Mitochondrial regulation of oxygen sensing. Mitochondrion. 5: 322-32
Emerling BM, Chandel NS. (2005) Oxygen sensing: getting pumped by sterols. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe30
Emerling BM, Platanias LC, Black E, et al. (2005) Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Molecular and Cellular Biology. 25: 4853-62
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