Shuyang Chen, Ph.D.

Affiliations: 
2015 Biological Sciences Drexel University, Philadelphia, PA, United States 
Area:
Biochemistry, Molecular Biology
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"Shuyang Chen"
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Nianli Sang grad student 2015 Drexel
 (AMPK-HDAC5 Pathway Facilitates Nuclear Accumulation of HIF-1alpha and Functional Activation of HIF-1 by Deacetylating Hsp70 in the Cytosol.)
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Publications

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He H, Qie S, Guo Q, et al. (2019) Stanniocalcin 2 (STC2) expression promotes post-radiation survival, migration and invasion of nasopharyngeal carcinoma cells. Cancer Management and Research. 11: 6411-6424
He D, Yin C, Qie S, et al. (2017) Abstract 3562: A novel TGF-β signaling pathway promotes a slow growing phenotype of cancer cells in response to glutamine insufficiency Cancer Research. 77: 3562-3562
Yin C, He D, Chen S, et al. (2016) Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate. Oncotarget
Chen S, Sang N. (2016) Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells. Journal of Cellular Biochemistry. 117: 267-78
Yin C, He D, Chen S, et al. (2016) Abstract 2802: Exogenous pyruvate supports oxygen-independent tumor cell proliferation by serving as an oxygen surrogate to maintain homeostasis of NAD+/NADH Cancer Research. 76: 2802-2802
Chen S, Yin C, Lao T, et al. (2015) AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol. Cell Cycle (Georgetown, Tex.). 1-17
Lin A, Truong B, Pappas A, et al. (2015) Uniform Nanosecond Pulsed Dielectric Barrier Discharge Plasma Enhances Anti-Tumor Effects by Induction of Immunogenic Cell Death in Tumors and Stimulation of Macrophages Plasma Processes and Polymers. 12: 1392-1399
Chen S, Yin C, Lao T, et al. (2014) Abstract LB-124: Histone deacetylase 5 stabilizes HIF-1α through Hsp70 deacetylation in cytosol Cancer Research. 74
Lao T, Chen S, Sang N. (2012) Two mutations impair the stability and function of ubiquitin-activating enzyme (E1). Journal of Cellular Physiology. 227: 1561-8
Chen S, Ying C, Liang D, et al. (2012) Abstract 4733: Function of cytoplasmic histone deacetylase 5 is required for HIF-1α stability Cancer Research. 72: 4733-4733
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