Christopher C. Kloss, Ph.D.
Affiliations: | 2013 | Weill Cornell Medical College, New York, NY, United States |
Area:
Inorganic Chemistry, Oncology, Biomedical EngineeringGoogle:
"Christopher Kloss"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Michel Sadelcuh | grad student | 2013 | Weill Cornell Medical College | |
| (Generation of chimeric antigen receptor modified human T lymphocytes for the potent and dual-antigen selective eradication of human cancers in mice.) | ||||
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Publications
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| Ramalingam P, Poulos MG, Lazzari E, et al. (2020) Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF. Nature Communications. 11: 666 |
| Castellarin M, Watanabe K, June CH, et al. (2018) Driving cars to the clinic for solid tumors. Gene Therapy |
| Wertheimer T, Velardi E, Tsai J, et al. (2018) Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration. Science Immunology. 3 |
| Zhao Z, Condomines M, van der Stegen SJ, et al. (2015) Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells. Cancer Cell. 28: 415-28 |
| Johnson LA, Scholler J, Ohkuri T, et al. (2015) Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma. Science Translational Medicine. 7: 275ra22 |
| Poulos MG, Gars EJ, Gutkin MC, et al. (2014) Activation of the vascular niche supports leukemic progression and resistance to chemotherapy. Experimental Hematology. 42: 976-86.e1-3 |
| Fedorov VD, Sadelain M, Kloss CC. (2014) Novel approaches to enhance the specificity and safety of engineered T cells. Cancer Journal (Sudbury, Mass.). 20: 160-5 |
| Wertheimer T, Kloss CC, Velardi E, et al. (2014) Endothelial Cells Promote Endogenous Thymic Regeneration after Injury Via BMP4 Signaling Blood. 124: 2429-2429 |
| Themeli M, Kloss CC, Ciriello G, et al. (2013) Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy. Nature Biotechnology. 31: 928-33 |
| Davila ML, Kloss CC, Gunset G, et al. (2013) CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia. Plos One. 8: e61338 |