Mona E. Aboutabl, Ph.D.

Affiliations: 
2011 University of Alberta, Edmonton, Alberta, Canada 
Area:
Pharmacy
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"Mona Aboutabl"
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Ayman El-Kadi grad student 2011 University of Alberta
 (Role of cytochrome P450-mediated arachidonic acid metabolites in the pathogenesis of cardiac hypertrophy.)
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Publications

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Tse MM, Aboutabl ME, Althurwi HN, et al. (2013) Cytochrome P450 epoxygenase metabolite, 14,15-EET, protects against isoproterenol-induced cellular hypertrophy in H9c2 rat cell line. Vascular Pharmacology. 58: 363-73
El-Sherbeni AA, Aboutabl ME, Zordoky BN, et al. (2013) Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics. The Aaps Journal. 15: 112-22
Zordoky BN, Anwar-Mohamed A, Aboutabl ME, et al. (2011) Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1440-50
Aboutabl ME, Zordoky BN, Hammock BD, et al. (2011) Inhibition of soluble epoxide hydrolase confers cardioprotection and prevents cardiac cytochrome P450 induction by benzo(a)pyrene. Journal of Cardiovascular Pharmacology. 57: 273-81
Anwar-mohamed A, Zordoky BN, Aboutabl ME, et al. (2010) Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation. Pharmacological Research. 61: 410-8
Zordoky BN, Anwar-Mohamed A, Aboutabl ME, et al. (2010) Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats. Toxicology and Applied Pharmacology. 242: 38-46
Aboutabl ME, Zordoky BN, El-Kadi AO. (2009) 3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats. British Journal of Pharmacology. 158: 1808-19
Zordoky BN, Aboutabl ME, El-Kadi AO. (2008) Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2277-86
Aboutabl ME, El-Kadi AO. (2007) Constitutive expression and inducibility of CYP1A1 in the H9c2 rat cardiomyoblast cells. Toxicology in Vitro : An International Journal Published in Association With Bibra. 21: 1686-91
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