Jennifer R. Mazzone, Ph.D.

Affiliations: 
2011 University of New Hampshire, Durham, NH, United States 
Area:
Organic Chemistry
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Charles Kent Zercher grad student 2011 UNH
 (I. The synthesis of papyracillic acids: Application of the tandem chain extension-acylation reaction. II. Diastereoselective synthesis of beta-methyl-gamma-keto esters through the utility of an L-serine auxiliary.)
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Publications

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Henderson CS, Mazzone JR, Moore AM, et al. (2021) Tandem Homologation-Acylation Chemistry: Single and Double Homologation. Tetrahedron. 91
Roy S, Kapoor A, Zhu F, et al. (2020) Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition. The Journal of Biological Chemistry
Fox JM, Moynihan JR, Mott BT, et al. (2016) Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs. Oncotarget
Conyers RC, Mazzone JR, Tripathi AK, et al. (2015) Antimalarial chemotherapy: orally curative artemisinin-derived trioxane dimer esters. Bioorganic & Medicinal Chemistry Letters. 25: 245-8
Mazzone JR, Conyers RC, Tripathi AK, et al. (2014) Antimalarial chemotherapy: artemisinin-derived dimer carbonates and thiocarbonates. Bioorganic & Medicinal Chemistry Letters. 24: 2440-3
Conyers RC, Mazzone JR, Siegler MA, et al. (2014) The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether. Bioorganic & Medicinal Chemistry Letters. 24: 1285-9
Mazzone JR, Zercher CK. (2012) Syntheses of papyracillic acids: Application of the tandem chain extension-acylation reaction Journal of Organic Chemistry. 77: 9171-9178
Jacobine AM, Mazzone JR, Slack RD, et al. (2012) Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose. Journal of Medicinal Chemistry. 55: 7892-9
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