☰ Chemistry Tree

Dale F. Mierke, Ph.D.

Affiliations:

Chemistry

Dartmouth College, Hanover, NH, United States

Area:

Biophysical chemistry, high resolution NMR, peptide hormone structure and function

Website:

http://www.dartmouth.edu/~chem/faculty/dfm.html

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Mean distance: 8.25

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Parents

Murray Goodman	grad student	1988	UCSD
(Nuclear magnetic resonance studies and computer simulations of biologically active peptides)
Horst C. Kessler	post-doc	1990-1993	Technical University of Munich

Children

Alexander E. Kelly	research assistant	1998	Clark University (Cell Biology Tree)
Christopher O. Audu	grad student	2013	Dartmouth

Collaborators

BETA: Related publications

Publications

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Barczewski AH, Ragusa MJ, Mierke DF, et al. (2019) Production, Crystallization, and Structure Determination of the IKK-binding Domain of NEMO. Journal of Visualized Experiments : Jove
Barczewski AH, Ragusa MJ, Mierke DF, et al. (2019) The IKK-binding domain of NEMO is an irregular coiled coil with a dynamic binding interface. Scientific Reports. 9: 2950
Busatto N, Salvagnin U, Resentini F, et al. (2017) The Peach RGF/GLV Signaling Peptide pCTG134 Is Involved in a Regulatory Circuit That Sustains Auxin and Ethylene Actions. Frontiers in Plant Science. 8: 1711
Privett B, Pellegrini M, Kovacikova G, et al. (2017) Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae. Biochemistry
Zheng F, Jewell H, Fitzpatrick J, et al. (2015) Computational design of selective peptides to discriminate between similar PDZ domains in an oncogenic pathway. Journal of Molecular Biology. 427: 491-510
Yu J, Rupasinghe C, Wilson JL, et al. (2015) Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. Chemical Biology & Drug Design. 85: 586-97
Guo B, Audu CO, Cochran JC, et al. (2014) Protein engineering of the N-terminus of NEMO: structure stabilization and rescue of IKKÎ² binding. Biochemistry. 53: 6776-85
Fitzpatrick JM, Pellegrini M, Cushing PR, et al. (2014) Small molecule inhibition of the Na(+)/H(+) exchange regulatory factor 1 and parathyroid hormone 1 receptor interaction. Biochemistry. 53: 5916-22
Audu CO, Plati JJ, Pellegrini M, et al. (2014) Engineering a soluble parathyroid hormone GPCR mimetic. Proteins. 82: 1370-5
Weiner JA, Audu CO, Seitler K, et al. (2014) Engineering the Endothelin A and B Receptors using a Soluble Template for Structural Analysis and Small Molecule Screening Biophysical Journal. 106: 102a-103a

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