Michael J. Hitchler, Ph.D.

Affiliations: 
2008 University of Iowa, Iowa City, IA 
Area:
Oncology
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"Michael Hitchler"
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Frederick E. Domann grad student 2008 University of Iowa
 (Epigenetic regulation of manganese superoxide dismutase in human breast cancer.)
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Publications

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Jiménez-Chillarón JC, Nijland MJ, Ascensão AA, et al. (2015) Back to the future: transgenerational transmission of xenobiotic-induced epigenetic remodeling. Epigenetics : Official Journal of the Dna Methylation Society. 10: 259-73
Biancolella M, Fortini BK, Tring S, et al. (2014) Identification and characterization of functional risk variants for colorectal cancer mapping to chromosome 11q23.1. Human Molecular Genetics. 23: 2198-209
Hitchler MJ, Domann FE. (2014) Regulation of CuZnSOD and its redox signaling potential: implications for amyotrophic lateral sclerosis. Antioxidants & Redox Signaling. 20: 1590-8
Cyr AR, Hitchler MJ, Domann FE. (2013) Regulation of SOD2 in cancer by histone modifications and CpG methylation: closing the loop between redox biology and epigenetics. Antioxidants & Redox Signaling. 18: 1946-55
Hitchler MJ, Domann FE. (2012) Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome. Free Radical Biology & Medicine. 53: 2178-87
Brusslan JA, Rus Alvarez-Canterbury AM, Nair NU, et al. (2012) Genome-wide evaluation of histone methylation changes associated with leaf senescence in Arabidopsis. Plos One. 7: e33151
Hitchler MJ, Rice JC. (2011) Genome-wide epigenetic analysis of human pluripotent stem cells by ChIP and ChIP-Seq. Methods in Molecular Biology (Clifton, N.J.). 767: 253-67
Yu L, Hitchler MJ, Sun W, et al. (2009) AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes. Journal of Oncology. 2009: 780874
Woodfield GW, Hitchler MJ, Chen Y, et al. (2009) Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3672-9
Hitchler MJ, Domann FE. (2009) Metabolic defects provide a spark for the epigenetic switch in cancer. Free Radical Biology & Medicine. 47: 115-27
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