Sabine U. Vorrink, Ph.D.
Affiliations: | 2014 | Human Toxicology | University of Iowa, Iowa City, IA |
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Sign in to add mentor| Frederick E. Domann | grad student | 2014 | University of Iowa | |
| (Regulatory crosstalk and interference between the PCB 126 stimulated AHR and hypoxia stimulated HIF-1alpha signaling pathways.) | ||||
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| Bell CC, Lauschke VM, Vorrink SU, et al. (2017) Transcriptional, functional and mechanistic comparisons of stem cell-derived hepatocytes, HepaRG cells and 3D human hepatocyte spheroids as predictive in vitro systems for drug-induced liver injury. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| Xiao W, Son J, Vorrink SU, et al. (2015) Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicology Letters. 233: 258-66 |
| Hallberg AR, Vorrink SU, Hudachek DR, et al. (2014) Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma. Epigenetics. 9: 1641-7 |
| Vorrink SU, Hudachek DR, Domann FE. (2014) Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). International Journal of Molecular Sciences. 15: 13916-31 |
| Vorrink SU, Sarsour EH, Olivier AK, et al. (2014) PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 377-82 |
| Vorrink SU, Domann FE. (2014) Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node. Chemico-Biological Interactions. 218: 82-8 |
| Vorrink SU, Severson PL, Kulak MV, et al. (2014) Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicology and Applied Pharmacology. 274: 408-16 |
| Place TL, Fitzgerald MP, Venkataraman S, et al. (2011) Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. Plos One. 6: e14617 |