Sabine U. Vorrink, Ph.D.

Affiliations: 
2014 Human Toxicology University of Iowa, Iowa City, IA 
Area:
Toxicology
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Frederick E. Domann grad student 2014 University of Iowa
 (Regulatory crosstalk and interference between the PCB 126 stimulated AHR and hypoxia stimulated HIF-1alpha signaling pathways.)
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Publications

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Lauschke VM, Vorrink SU, Moro SM, et al. (2016) Massive rearrangements of cellular miRNA signatures are key drivers of hepatocyte dedifferentiation. Hepatology (Baltimore, Md.)
Xiao W, Son J, Vorrink SU, et al. (2015) Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicology Letters. 233: 258-66
Hallberg AR, Vorrink SU, Hudachek DR, et al. (2014) Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma. Epigenetics. 9: 1641-7
Vorrink SU, Hudachek DR, Domann FE. (2014) Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3',4,4',5-pentachlorobiphenyl (PCB 126). International Journal of Molecular Sciences. 15: 13916-31
Vorrink SU, Sarsour EH, Olivier AK, et al. (2014) PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 377-82
Vorrink SU, Domann FE. (2014) Regulatory crosstalk and interference between the xenobiotic and hypoxia sensing pathways at the AhR-ARNT-HIF1α signaling node. Chemico-Biological Interactions. 218: 82-8
Adamcakova-Dodd A, Stebounova LV, Kim JS, et al. (2014) Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models. Particle and Fibre Toxicology. 11: 15
Vorrink SU, Severson PL, Kulak MV, et al. (2014) Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines. Toxicology and Applied Pharmacology. 274: 408-16
Place TL, Fitzgerald MP, Venkataraman S, et al. (2011) Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. Plos One. 6: e14617
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