Edward C. Thornborrow, Ph.D.
Affiliations: | 2001 | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
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Molecular BiologyGoogle:
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Parents
Sign in to add mentorJames J. Manfredi | grad student | 2001 | Mount Sinai School of Medicine | |
(Transcriptional regulation of the proapoptotic bax gene by the tumor suppressor protein p53.) |
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Publications
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Thornborrow EC, Maurer M, Manfredi JJ. (2003) Electrophoretic mobility shift analysis of the DNA binding of tumor suppressor gene products. Methods in Molecular Biology (Clifton, N.J.). 223: 87-100 |
Thornborrow EC, Patel S, Mastropietro AE, et al. (2002) A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes. Oncogene. 21: 990-9 |
Thornborrow EC, Manfredi JJ. (2001) The tumor suppressor protein p53 requires a cofactor to activate transcriptionally the human BAX promoter. The Journal of Biological Chemistry. 276: 15598-608 |
Thornborrow EC, Manfredi JJ. (1999) One mechanism for cell type-specific regulation of the bax promoter by the tumor suppressor p53 is dictated by the p53 response element. The Journal of Biological Chemistry. 274: 33747-56 |