Sukrutha U. Chettimada, Ph.D.

Affiliations: 
2013 College of Medicine University of South Alabama, Mobile, AL, United States 
Area:
Biochemistry, Molecular Biology, Medicine and Surgery, Cell Biology
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"Sukrutha Chettimada"
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Sachin A. Gupte grad student 2013 University of South Alabama
 (Role of glucose-6-phosphate dehydrogenase in modulating pulmonary artery smooth muscle and progenitor cells function.)
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Publications

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Ochi R, Chettimada S, Kizub I, et al. (2018) Dehydroepiandrosterone (DHEA) inhibits I and window current by voltage-dependent and independent mechanisms in arterial smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology
Ochi R, Chettimada S, Gupte SA. (2018) DHEA-Induced Inhibition of I CaL in Arterial Smooth Muscle Cells. Involvement of Glucose-6-Phosphate Dehydrogenase and GPCR Signaling Biophysical Journal. 114
Ochi R, Chettimada S, Gupte SA. (2017) Hydrogen Peroxide Inhibits Whole-Cell ICa,L but Increases on-Cell ICa,L and Ebselen, an Organoselenium Compound, Suppresses ICa,L in Arterial Smooth Muscle Cells Biophysical Journal. 112: 244
Chettimada S, Joshi SR, Dhagia V, et al. (2016) Vascular smooth muscle cell contractile protein expression is increased through PKG-dependent and -independent pathways by G6PD inhibition and deficiency. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00335.2016
Chettimada S, Gupte R, Rawat D, et al. (2015) Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 308: L287-300
Rawat DK, Alzoubi A, Gupte R, et al. (2014) Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure. Hypertension. 64: 1266-74
Haspel JA, Chettimada S, Shaik RS, et al. (2014) Circadian rhythm reprogramming during lung inflammation. Nature Communications. 5: 4753
Ochi R, Chettimada S, Gupte SA. (2014) Poly(ethylene glycol)-cholesterol inhibits L-type Ca2+ channel currents and augments voltage-dependent inactivation in A7r5 cells. Plos One. 9: e107049
Chettimada S, Joshi SR, Alzoubi A, et al. (2014) Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L545-56
Chettimada S, Ata H, Rawat DK, et al. (2014) Contractile protein expression is upregulated by reactive oxygen species in aorta of Goto-Kakizaki rat. American Journal of Physiology. Heart and Circulatory Physiology. 306: H214-24
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