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Tony W. Li, Ph.D.

Affiliations: 
2004 University of California, Irvine, Irvine, CA 
Area:
Molecular Biology
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Marian L. Waterman grad student 2004 UC Irvine
 (Expression and chromatin structure of the intronic lymphoid enhancer factor-1 promoter.)

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Peng H, Li TW, Yang H, et al. (2015) Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells. The American Journal of Pathology. 185: 1135-44
Li TW, Peng H, Yang H, et al. (2015) S-Adenosylmethionine and methylthioadenosine inhibit β-catenin signaling by multiple mechanisms in liver and colon cancer. Molecular Pharmacology. 87: 77-86
Li TW, Yang H, Peng H, et al. (2012) Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice. Carcinogenesis. 33: 427-35
Yang H, Li TW, Peng J, et al. (2011) Insulin-like growth factor 1 activates methionine adenosyltransferase 2A transcription by multiple pathways in human colon cancer cells. The Biochemical Journal. 436: 507-16
Li TW, Ting JH, Yokoyama NN, et al. (2006) Wnt activation and alternative promoter repression of LEF1 in colon cancer. Molecular and Cellular Biology. 26: 5284-99
Atcha FA, Munguia JE, Li TW, et al. (2003) A new beta-catenin-dependent activation domain in T cell factor. The Journal of Biological Chemistry. 278: 16169-75
Li B, Mackay DR, Dai Q, et al. (2002) The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 99: 6064-9
Hovanes K, Li TW, Munguia JE, et al. (2001) Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nature Genetics. 28: 53-7
Hovanes K, Li TW, Waterman ML. (2000) The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing. Nucleic Acids Research. 28: 1994-2003
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