Kira T. Pate, Ph.D.

Affiliations: 
2012 Biomedical Sciences - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Molecular Biology, Cell Biology, Biochemistry, Oncology
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"Kira Pate"
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Parents

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Marian L. Waterman grad student 2012 UC Irvine
 (Expression and Actions of LEF/TCFs in Colon Cancer.)
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Publications

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Lyou Y, Habowski A, Sprowl-Tanio S, et al. (2017) Abstract 5494: Hypoxia via HIF1alpha can regulate Wnt signaling in human colon cancer cells Cancer Research. 77: 5494-5494
Sprowl-Tanio S, Habowski AN, Pate KT, et al. (2016) Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer. Cancer & Metabolism. 4: 20
Pate KT, Stringari C, Sprowl-Tanio S, et al. (2014) Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer. The Embo Journal. 33: 1454-73
Chodaparambil JV, Pate KT, Hepler MR, et al. (2014) Molecular functions of the TLE tetramerization domain in Wnt target gene repression. The Embo Journal. 33: 719-31
Chen GT, Lee M, Pate K, et al. (2014) Abstract 138: A role for Wnt signaling in regulation of Warburg metabolism in colon cancer Cancer Research. 74: 138-138
Stringari C, Pate KT, Edwards RA, et al. (2013) Metabolic Imaging of Colon Cancer Tumors In Vivo by Phasor Fluorescence Lifetime Microscopy of NADH Biophysical Journal. 104: 342a-343a
Stringari C, Edwards RA, Pate KT, et al. (2012) Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH. Scientific Reports. 2: 568
Stringari C, Edwards R, Watermen M, et al. (2012) In Vivo Metabolic Mapping of Stem Cells and Differentiated Progeny in Small Intestine and Colon Crypts by Phasor Fluorescence Lifetime Microscopy Biophysical Journal. 102: 618a
Yokoyama NN, Pate KT, Sprowl S, et al. (2010) A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer. Nucleic Acids Research. 38: 6375-88
Sikandar SS, Pate KT, Anderson S, et al. (2010) NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. Cancer Research. 70: 1469-78
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