Parents

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Joseph E Varner grad student 1960 Ohio State (Plant Biology Tree)
 (he Cause of Cellular Senescence and Its Prevention)
George C. Webster grad student 1960 Ohio State (Plant Biology Tree)
James Frederick Bonner post-doc 1960-1965 Caltech (Neurotree)

Children

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Ibrahim S. Abd-Elazem grad student 2002 Johns Hopkins (Microtree)
Jonathan D. Heller grad student 2003 Johns Hopkins
Chih-Chuan Chang grad student 2006 Johns Hopkins
William F. Marzluff post-doc Johns Hopkins (Chemistry Tree)
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Publications

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Lin YL, Tsai NM, Hsieh CH, et al. (2016) In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway. Proceedings of the National Academy of Sciences of the United States of America
Huang RC, Chang CC, Mold D. (2006) Survivin-dependent and -independent pathways and the induction of cancer cell death by tetra-O-methyl nordihydroguaiaretic acid. Seminars in Oncology. 33: 479-85
Chang CC, Liang YC, Klutz A, et al. (2006) Reversal of multidrug resistance by two nordihydroguaiaretic acid derivatives, M4N and maltose-M3N, and their use in combination with doxorubicin or paclitaxel. Cancer Chemotherapy and Pharmacology. 58: 640-53
Park R, Chang CC, Liang YC, et al. (2005) Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4601-9
Chang CC, Heller JD, Kuo J, et al. (2004) Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression. Proceedings of the National Academy of Sciences of the United States of America. 101: 13239-44
Huang RC, Li Y, Giza PE, et al. (2003) Novel antiviral agent tetraglycylated nordihydroguaiaretic acid hydrochloride as a host-dependent viral inhibitor. Antiviral Research. 58: 57-64
Abd-Elazem IS, Chen HS, Bates RB, et al. (2002) Isolation of two highly potent and non-toxic inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase from Salvia miltiorrhiza. Antiviral Research. 55: 91-106
Heller JD, Kuo J, Wu TC, et al. (2001) Tetra-O-methyl nordihydroguaiaretic acid induces G2 arrest in mammalian cells and exhibits tumoricidal activity in vivo. Cancer Research. 61: 5499-504
Marzluff WF, White EL, Benjamin R, et al. (1975) Low molecular weight RNA species from chromatin. Biochemistry. 14: 3715-24
Marzluff WF, Huang RC. (1975) Chromatin directed transcription of 5S and tRNA genes. Proceedings of the National Academy of Sciences of the United States of America. 72: 1082-6
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