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Stephen B. H. Kent

Chemistry University of Chicago, Chicago, IL 
total synthesis of proteins to apply advanced physical methods to understand the chemical basis of protein function
"Stephen Kent"
Mean distance: 7.83


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Richard Hodges grad student 1968-1970 Massey University (New Zealand)
 (Peptide sequences by mass spectrometry)
Douglas T. Browne grad student 1975 UC Berkeley
 (Specific chemical modification and ¹³C-nmr properties of the lysine at the active site of alcohol dehydrogenase)
R. Bruce Merrifield post-doc 1975-1978 Rockefeller
 (Side reactions in solid phase peptide synthesis; physicochemical properties of the peptide-resin)


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Darren A. Thompson research assistant 1996-1998 Gryphon Sciences
Philip E. Dawson grad student 1993-1996 Scripps Research Institute
Duhee Bang grad student 2005 Chicago
Erik C. Johnson grad student 2006 Chicago
David J. Boerema grad student 2007 Chicago
Brad L. Pentelute grad student 2008 Chicago
Vladimir Torbeev grad student 2009 Chicago
Fangkun Deng grad student 2013 Chicago
Michal Avital Shmilovici grad student 2014 Chicago
Zachary P. Gates grad student 2014 Chicago
Bobo Dang grad student 2015 Chicago
Louis Y P Luk post-doc Chicago
Junliang Zhang post-doc
Thomas W. Muir post-doc 1992-1995 Scripps Institute
Michael C. Fitzgerald post-doc 1994-1998 Scripps Institute
Laurie L. Parker post-doc 2003-2008 Chicago
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Marinec PS, Landgraf KE, Uppalapati M, et al. (2021) A Non-immunogenic Bivalent d-Protein Potently Inhibits Retinal Vascularization and Tumor Growth. Acs Chemical Biology
Kumar M, Mandal K, Blakeley MP, et al. (2020) Visualizing Tetrahedral Oxyanion Bound in HIV-1 Protease Using Neutrons: Implications for the Catalytic Mechanism and Drug Design. Acs Omega. 5: 11605-11617
Torbeev V, Kent SBH. (2020) Chemical Synthesis of an Enzyme Containing an Artificial Catalytic Apparatus Australian Journal of Chemistry. 73: 321-326
Donovan AJ, Dowle J, Yang Y, et al. (2020) Total synthesis of bovine pancreatic trypsin inhibitor and the protein diastereomer [ Gly37D‐Ala ] BPTI using Boc chemistry solid phase peptide synthesis Peptide Science. 112
Kent SBH. (2018) Novel Protein Science Enabled by Total Chemical Synthesis. Protein Science : a Publication of the Protein Society
Kent S. (2017) Chemical protein synthesis: Inventing synthetic methods to decipher how proteins work. Bioorganic & Medicinal Chemistry. 25: 4926-4937
Dang B, Chhabra S, Pennington MW, et al. (2017) Reinvestigation of the biological activity of D-allo-ShK protein. The Journal of Biological Chemistry
Kubota T, Durek T, Dang B, et al. (2017) Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the United States of America
Dang B, Shen R, Kubota T, et al. (2017) Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angewandte Chemie (International Ed. in English)
Gates ZP, Baxa MC, Yu W, et al. (2017) Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core. Proceedings of the National Academy of Sciences of the United States of America
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