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Stephen B. H. Kent

Chemistry University of Chicago, Chicago, IL 
total synthesis of proteins to apply advanced physical methods to understand the chemical basis of protein function
"Stephen Kent"
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Douglas T. Browne grad student 1975 UC Berkeley
 (Specific chemical modification and ¹³C-nmr properties of the lysine at the active site of alcohol dehydrogenase)
R. Bruce Merrifield post-doc 1975-1978 Rockefeller


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Darren A. Thompson research assistant 1996-1998 Chicago
Louis Y P Luk grad student Chicago
Philip E. Dawson grad student 1993-1996 Scripps Research Institute
Duhee Bang grad student 2005 Chicago
Erik C. Johnson grad student 2006 Chicago
David J. Boerema grad student 2007 Chicago
Brad L. Pentelute grad student 2008 Chicago
Vladimir Torbeev grad student 2009 Chicago
Fangkun Deng grad student 2013 Chicago
Michal Avital Shmilovici grad student 2014 Chicago
Zachary P. Gates grad student 2014 Chicago
Bobo Dang grad student 2015 Chicago
Junliang Zhang post-doc
Thomas W. Muir post-doc 1996 Scripps Institute
Michael C. Fitzgerald post-doc 1994-1998 Scripps Institute
Laurie L. Parker post-doc 2003-2008 Chicago
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Kent SBH. (2018) Novel Protein Science Enabled by Total Chemical Synthesis. Protein Science : a Publication of the Protein Society
Dang B, Chhabra S, Pennington MW, et al. (2017) Reinvestigation of the biological activity of D-allo-ShK protein. The Journal of Biological Chemistry
Kubota T, Durek T, Dang B, et al. (2017) Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the United States of America
Dang B, Shen R, Kubota T, et al. (2017) Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angewandte Chemie (International Ed. in English)
Gates ZP, Baxa MC, Yu W, et al. (2017) Perplexing cooperative folding and stability of a low-sequence complexity, polyproline 2 protein lacking a hydrophobic core. Proceedings of the National Academy of Sciences of the United States of America
Kent S, Dhayalan B, Mandal K, et al. (2016) Scope & Limitations of Fmoc Chemistry SPPS-Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin. Chemistry (Weinheim An Der Bergstrasse, Germany)
Gates ZP, Dhayalan B, Kent SB. (2016) Obviation of hydrogen fluoride in Boc chemistry solid phase peptide synthesis of peptide-(α)thioesters. Chemical Communications (Cambridge, England)
Boerema DJ, Tereshko VA, Zhang J, et al. (2016) Chemical synthesis and enzymatic properties of RNase A analogues designed to enhance second-step catalytic activity. Organic & Biomolecular Chemistry. 14: 8804-8814
Dang B, Kubota T, Mandal K, et al. (2016) Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angewandte Chemie (International Ed. in English)
Castillo JP, Sánchez-Rodríguez JE, Hyde HC, et al. (2016) β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel. Proceedings of the National Academy of Sciences of the United States of America
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