Felicia A. Etzkorn, Ph.D.
Affiliations: | 1993-2000 | Chemistry | University of Virginia, Charlottesville, VA |
2000- | Chemistry | Virginia Polytechnic Institute and State University, Blacksburg, VA, United States |
Area:
protein structure and enzyme inhibitors by designing and synthesizing conformationally constrained mimics of peptidesWebsite:
http://www.etzkornlab.chem.vt.edu/Google:
"Felicia Etzkorn"Bio:
Mean distance: 7.16 | S | N | B | C | P |
Parents
Sign in to add mentorJames F. Hinton | research assistant | 1977 | University of Arkansas, Fayetteville | |
Paul Allan Bartlett | grad student | 1991 | UC Berkeley | |
(Design, synthesis and evaluation of tendamistat mimics : inhibitors of a-amylase) | ||||
Christopher T. Walsh | post-doc | 1991-1993 | Harvard Medical School |
Children
Sign in to add traineeLuke Wiseman | research assistant | 2000 | UVA |
Jennifer L. Stockdill | research assistant | 2001-2002 | Virginia Tech |
Matthew D. Shoulders | research assistant | 2004 | Virginia Tech |
Scott A. Hart | grad student | 2000 | UVA |
Tobin J. Dickerson | grad student | 1999-2000 | UVA |
Tao Liu | grad student | 2007 | Virginia Tech |
Song Zhao | grad student | 2007 | Virginia Tech |
Nan Dai | grad student | 2008 | Virginia Tech |
Galina Kapustina | post-doc | 2000-2003 | Virginia Tech |
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Publications
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Mayfield JE, Fan S, Wei S, et al. (2015) Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chemical Biology |
Etzkorn FA, Zhao S. (2015) Stereospecific phosphorylation by the central mitotic kinase Cdk1-cyclin B. Acs Chemical Biology. 10: 952-6 |
Mercedes-Camacho AY, Mullins AB, Mason MD, et al. (2013) Kinetic isotope effects support the twisted amide mechanism of Pin1 peptidyl-prolyl isomerase. Biochemistry. 52: 7707-13 |
Nachman RJ, Wang XJ, Etzkorn FA, et al. (2013) Evaluation of insect CAP2b analogs with either an (E)-alkene, trans- or a (Z)-alkene, cis-Pro isostere identifies the Pro orientation for antidiuretic activity in the stink bug. Peptides. 41: 101-6 |
Xu GG, Slebodnick C, Etzkorn FA. (2012) Cyclohexyl ketone inhibitors of Pin1 dock in a trans-diaxial cyclohexane conformation. Plos One. 7: e44226 |
Zhang M, Wang XJ, Chen X, et al. (2012) Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code. Acs Chemical Biology. 7: 1462-70 |
Tarrant MK, Rho HS, Xie Z, et al. (2012) Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis. Nature Chemical Biology. 8: 262-9 |
Xu GG, Zhang Y, Mercedes-Camacho AY, et al. (2011) A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state. Biochemistry. 50: 9545-50 |
Namanja AT, Wang XJ, Xu B, et al. (2011) Stereospecific gating of functional motions in Pin1. Proceedings of the National Academy of Sciences of the United States of America. 108: 12289-94 |
Namanja AT, Wang XJ, Xu B, et al. (2010) Toward flexibility-activity relationships by NMR spectroscopy: dynamics of Pin1 ligands. Journal of the American Chemical Society. 132: 5607-9 |