Hendrik Luesch

Affiliations:

University of Florida, Gainesville, Gainesville, FL, United States

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Parents

Richard E. Moore	grad student	1997-2002	University of Hawai'i at Manoa
(The search for new anticancer drugs from marine cyanobacteria and investigations on the biosynthesis of cyanobacterial metabolites.)
Peter G. Schultz	post-doc	2002-2005	Scripps Research Institute

Children

Fatma H. Al-Awadhi	grad student	2012-	University of Florida
Weijing Cai	grad student	2012-	University of Florida
Danmeng Luo	grad student	2013-	University of Florida
Lorelie Imperial	grad student	2014-	University of Florida
Xiao Liang	grad student	2014-	University of Florida
Kara Spencer	grad student	2015-	University of Florida
Kanchan Taori	grad student	2006-2008	University of Florida
Jason C. Kwan	grad student	2005-2010	University of Florida
Rui Wang	grad student	2007-2012	University of Florida
Kamolrat Metavarayuth	grad student	2010-2012	University of Florida
Rana Montaser	grad student	2008-2013	University of Florida
Lilibeth A. Salvador	grad student	2008-2013	University of Florida
Michelle S. Bousquet	grad student	2010-2015	University of Florida
Khanh Ha	grad student	2014-2016	University of Florida
Dimitris Kallifidas	post-doc	2013-	University of Florida
James H. Matthews	post-doc	2015-	University of Florida
Susan Matthew	post-doc	2006-2009	University of Florida
Yanxia Liu	post-doc	2006-2010	University of Florida
Ranjala Ratnayake	post-doc	2009-2011	University of Florida
Qi-Yin Chen	post-doc	2008-2012	University of Florida

Collaborators

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Publications

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Elsadek LA, Matthews JH, Nishimura S, et al. (2021) Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A. Chembiochem : a European Journal of Chemical Biology
Grenning AJ, Emmetiere F, Ratnayake R, et al. (2021) Function-oriented and modular (+/-)-cis-pseudoguaianolide synthesis: Discovery of new Nrf2 Activators and NF-κB Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany)
Liang X, Chen QY, Seabra GM, et al. (2021) Bifunctional Doscadenamides Activate Quorum Sensing in Gram-Negative Bacteria and Synergize with TRAIL to Induce Apoptosis in Cancer Cells. Journal of Natural Products
Lizarme-Salas Y, Ariawan AD, Ratnayake R, et al. (2020) Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity. Beilstein Journal of Organic Chemistry. 16: 2663-2670
Chen QY, Luo D, Seabra GM, et al. (2020) Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7. Bioorganic & Medicinal Chemistry. 28: 115756
Nasser AA, Eissa IH, Oun MR, et al. (2020) Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFR and EGFR. Organic & Biomolecular Chemistry
Jiang G, Zhang P, Ratnayake R, et al. (2020) Fungal epithiodiketopiperazines carrying α,β-polysulfide bridges from Penecillium steckii YE, and their chemical interconversion. Chembiochem : a European Journal of Chemical Biology
Paciaroni NG, Norwood VM, Ratnayake R, et al. (2020) Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets. Bioorganic & Medicinal Chemistry. 28: 115546
Al-Awadhi FH, Salvador-Reyes LA, Elsadek LA, et al. (2020) Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases. Acs Chemical Neuroscience
Luesch H, MacMillan JB. (2020) Targeting and extending the eukaryotic druggable genome with natural products. Natural Product Reports. 37: 744-746