Hendrik Luesch

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
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"Hendrik Luesch"
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Parents

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Richard E. Moore grad student 1997-2002 University of Hawai'i at Manoa
 (The search for new anticancer drugs from marine cyanobacteria and investigations on the biosynthesis of cyanobacterial metabolites.)
Peter G. Schultz post-doc 2002-2005 Scripps Research Institute
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Publications

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Elsadek LA, Matthews JH, Nishimura S, et al. (2021) Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A. Chembiochem : a European Journal of Chemical Biology
Grenning AJ, Emmetiere F, Ratnayake R, et al. (2021) Function-oriented and modular (+/-)-cis-pseudoguaianolide synthesis: Discovery of new Nrf2 Activators and NF-κB Inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany)
Liang X, Chen QY, Seabra GM, et al. (2021) Bifunctional Doscadenamides Activate Quorum Sensing in Gram-Negative Bacteria and Synergize with TRAIL to Induce Apoptosis in Cancer Cells. Journal of Natural Products
Lizarme-Salas Y, Ariawan AD, Ratnayake R, et al. (2020) Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity. Beilstein Journal of Organic Chemistry. 16: 2663-2670
Chen QY, Luo D, Seabra GM, et al. (2020) Ahp-Cyclodepsipeptides as tunable inhibitors of human neutrophil elastase and kallikrein 7: Total synthesis of tutuilamide A, serine protease selectivity profile and comparison with lyngbyastatin 7. Bioorganic & Medicinal Chemistry. 28: 115756
Nasser AA, Eissa IH, Oun MR, et al. (2020) Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFR and EGFR. Organic & Biomolecular Chemistry
Jiang G, Zhang P, Ratnayake R, et al. (2020) Fungal epithiodiketopiperazines carrying α,β-polysulfide bridges from Penecillium steckii YE, and their chemical interconversion. Chembiochem : a European Journal of Chemical Biology
Paciaroni NG, Norwood VM, Ratnayake R, et al. (2020) Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets. Bioorganic & Medicinal Chemistry. 28: 115546
Al-Awadhi FH, Salvador-Reyes LA, Elsadek LA, et al. (2020) Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases. Acs Chemical Neuroscience
Luesch H, MacMillan JB. (2020) Targeting and extending the eukaryotic druggable genome with natural products. Natural Product Reports. 37: 744-746
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