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Lea M. Beaulieu, Ph.D.

Affiliations: 
2007 Pathology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pathology
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"Lea Beaulieu"
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Frank C. Church grad student 2007 UNC Chapel Hill
 (Role of the protein C system in breast cancer cell invasion and endothelial cell angiogenesis.)

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Publications

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Sladojevic N, Oh GT, Kim HH, et al. (2017) Decreased Thromboembolic Stroke but not Atherosclerosis or Vascular Remodeling in Mice with ROCK2-deficient Platelets. Cardiovascular Research
Beaulieu LM, Lin E, Mick E, et al. (2014) Interleukin 1 receptor 1 and interleukin 1β regulate megakaryocyte maturation, platelet activation, and transcript profile during inflammation in mice and humans. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 552-64
McManus DD, Beaulieu LM, Mick E, et al. (2013) Relationship among circulating inflammatory proteins, platelet gene expression, and cardiovascular risk. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2666-73
Risitano A, Beaulieu LM, Vitseva O, et al. (2012) Platelets and platelet-like particles mediate intercellular RNA transfer. Blood. 119: 6288-95
Beaulieu LM, Lin E, Morin KM, et al. (2011) Regulatory effects of TLR2 on megakaryocytic cell function. Blood. 117: 5963-74
Beaulieu LM, Freedman JE. (2010) p38: signaling improved platelet storage? Blood. 115: 1665-6
Beaulieu LM, Freedman JE. (2010) The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes. Thrombosis Research. 125: 205-9
Gramling MW, Beaulieu LM, Church FC. (2010) Activated protein C enhances cell motility of endothelial cells and MDA-MB-231 breast cancer cells by intracellular signal transduction. Experimental Cell Research. 316: 314-28
Rex S, Beaulieu LM, Perlman DH, et al. (2009) Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule release. Thrombosis and Haemostasis. 102: 97-110
Blair P, Rex S, Vitseva O, et al. (2009) Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. Circulation Research. 104: 346-54
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