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David J. Weber, Ph.D.

Affiliations: 
1992- Biochemistry and Molecular Biology University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
structure and function of S100B, a growth factor in the brain and skin
Website:
http://medschool.umaryland.edu/facultyresearchprofile/viewprofile.aspx?id=1438
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"David J. Weber"
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Parents

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Richard G. Hiskey grad student 1984-1988 UNC Chapel Hill
 (Investigation of Gla-domain Peptides of Prothrombin Binding to Synthetic Phospholipid Membranes)
Albert S. Mildvan post-doc 1988-1992 Johns Hopkins Medical School

Children

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Alexander C. Drohat grad student 1993-1997 University of Maryland Medical School
Todd C. Tenenholz grad student 1994-1998 University of Maryland Medical School
Karen C. Ellis grad student 2002 University of Maryland Medical School
Keith G. Inman grad student 2003 University of Maryland Medical School
Paul T. Wilder grad student 2004 University of Maryland Medical School
Kristen M. Varney grad student 1999-2004 University of Maryland Medical School
Ruiqing Yang grad student 2006 University of Maryland Medical School
Jing Lin grad student 2001-2006 University of Maryland Medical School
Nathan Thompson Wright grad student 2008 University of Maryland Medical School
Thomas H. Charpentier grad student 2009 University of Maryland Medical School
Michele B. Weiss grad student 2009 University of Maryland Medical School
Kira G. Hartman grad student 2012 University of Maryland Medical School
Melissa A. Liriano grad student 2012 University of Maryland Medical School
Laura E. McKnight grad student 2012 University of Maryland Medical School
Zephan Melville grad student 2012-2017 University of Maryland Medical School
Milad Alasady grad student 2014-2018 University of Maryland Medical School
Judy C. Amburgey post-doc University of Maryland Medical School
Dinendra Abeyawardhane post-doc 2019- University of Maryland Medical School
Richard R. Rustandi post-doc 1996-2000 University of Maryland Medical School
Michelle I. Vitolo post-doc 2007-2008 University of Maryland Medical School
Brian R. Cannon post-doc 2008-2011 University of Maryland Medical School
Raquel Godoy Ruiz post-doc 2011-2015 University of Maryland Medical School
Michael C. Cavalier post-doc 2012-2016 University of Maryland Medical School
Shardell Spriggs post-doc 2013-2016 University of Maryland Medical School
Sean D. Stowe post-doc 2013-2016 University of Maryland Medical School
Braden M. Roth post-doc 2014-2017 University of Maryland Medical School

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Publications

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Lázaro-Gorines R, Pérez P, Heras-Murillo I, et al. (2023) Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2304818
Abeyawardhane DL, Adipietro KA, Godoy-Ruiz R, et al. (2023) Endosomal activation of the binary toxin is Ca -dependent. Biorxiv : the Preprint Server For Biology
Thankan RS, Thomas E, Purushottamachar P, et al. (2023) Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse Model. Bioorganic Chemistry. 139: 106700
Chen X, Adhikary G, Newland JJ, et al. (2023) Transglutaminase 2 binds to the CD44v6 cytoplasmic domain to stimulate CD44v6/ERK1/2 signaling and maintain an aggressive cancer phenotype. Molecular Cancer Research : McR
O'Neal AJ, Singh N, Rolandelli A, et al. (2023) Croquemort elicits activation of the immune deficiency pathway in ticks. Proceedings of the National Academy of Sciences of the United States of America. 120: e2208673120
Yu W, Weber DJ, MacKerell AD. (2023) Integrated Covalent Drug Design Workflow Using Site Identification by Ligand Competitive Saturation. Journal of Chemical Theory and Computation
Thomas E, Thankan RS, Purushottamachar P, et al. (2023) Targeted Degradation of Androgen Receptor by VNPP433-3β in Castration-Resistant Prostate Cancer Cells Implicates Interaction with E3 Ligase MDM2 Resulting in Ubiquitin-Proteasomal Degradation. Cancers. 15
Karade SS, Franco EJ, Rojas AC, et al. (2023) Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum α-Glucosidase I with Anti-SARS-CoV-2 Activity. Journal of Medicinal Chemistry
Coburn KM, Roth B, Varney KM, et al. (2022) H, C, and N assignments of the mRNA binding protein hnRNP A18. Biomolecular Nmr Assignments
Yu W, Weber DJ, MacKerell AD. (2022) Computer-Aided Drug Design: An Update. Methods in Molecular Biology (Clifton, N.J.). 2601: 123-152
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