Daniel J. Leahy

Biophysics and Biophysical Chemistry Johns Hopkins University, Baltimore, MD 
Molecular studies of signal transduction
"Daniel J. Leahy"


Mean distance: 7.93


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Harden M. McConnell grad student 1988 Stanford
 (Construction of a system to study the antibody combining site by NMR)


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Jutta Beneken grad student 2001 Johns Hopkins
Charles E. Dann grad student 2002 Johns Hopkins
Brent Y. Hamaoka grad student 2006 Johns Hopkins
Jason S. McLellan grad student 2009 Johns Hopkins
Tzu-Lan Yeh grad student 2012 Johns Hopkins
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Kavran JM, Leahy DJ. (2015) Immunoaffinity Purification of Proteins. Methods in Enzymology. 559: 27-36
Li W, Koutmou KS, Leahy DJ, et al. (2015) Systemic RNA Interference Deficiency-1 (SID-1) extracellular domain selectively binds long double-stranded RNA and is required for RNA transport by SID-1. The Journal of Biological Chemistry
Zhang W, Wu J, Ward MD, et al. (2015) Structural basis of arc binding to synaptic proteins: implications for cognitive disease. Neuron. 86: 490-500
McCabe JM, Leahy DJ. (2015) Smoothened goes molecular: new pieces in the hedgehog signaling puzzle. The Journal of Biological Chemistry. 290: 3500-7
Ward MD, Leahy DJ. (2015) Kinase activator-receiver preference in ErbB heterodimers is determined by intracellular regions and is not coupled to extracellular asymmetry. The Journal of Biological Chemistry. 290: 1570-9
Cleveland TE, McCabe JM, Leahy DJ. (2014) Detergent-solubilized Patched purified from Sf9 cells fails to interact strongly with cognate Hedgehog or Ihog homologs. Protein Expression and Purification. 104: 92-102
Wang Y, Kavran JM, Chen Z, et al. (2014) Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation. The Journal of Biological Chemistry. 289: 31361-72
Ma HS, Nguyen B, Duffield AS, et al. (2014) FLT3 kinase inhibitor TTT-3002 overcomes both activating and drug resistance mutations in FLT3 in acute myeloid leukemia. Cancer Research. 74: 5206-17
Kavran JM, Leahy DJ. (2014) Silver staining of SDS-polyacrylamide gel. Methods in Enzymology. 541: 169-76
Kavran JM, Leahy DJ. (2014) Coupling antibody to cyanogen bromide-activated sepharose. Methods in Enzymology. 541: 27-34
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