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Guang Hu, Ph.D.

Affiliations: 
National Institute of Environmental Health Science, USA 
Area:
Stem Cell Biology
Website:
http://www.niehs.nih.gov/research/atniehs/labs/lmc/stemcell/index.cfm
Google:
"guang hu niehs"
Bio:

Guang Hu, Ph.D., leads the Stem Cell Biology Group within the Laboratory of Molecular Carcinogenesis. He earned his Ph.D. in 2003 at Baylor College of Medicine, Houston, Texas. Hu was a Helen Hay Whitney Foundation fellow from 2004 to 2007 and completed a postdoctoral fellowship at Harvard Medical School under Stephen Elledge, Ph.D., before joining NIEHS in 2009. He has published 13 peer-reviewed articles in leading biomedical journals during his graduate and postdoctoral work.


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Parents

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Theodore G. Wensel grad student 1998-2003 Baylor College of Medicine
Stephen J. Elledge post-doc 2009 Harvard Medical School

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Publications

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Brumbaugh J, Di Stefano B, Wang X, et al. (2018) Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling. Cell. 172: 629-631
Brumbaugh J, Di Stefano B, Wang X, et al. (2017) Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling. Cell
Borkent M, Bennett BD, Lackford B, et al. (2016) A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2. Stem Cell Reports
Seo M, Lee S, Kim JH, et al. (2014) RNAi-based functional selection identifies novel cell migration determinants dependent on PI3K and AKT pathways. Nature Communications. 5: 5217
Cinghu S, Yellaboina S, Freudenberg JM, et al. (2014) Integrative framework for identification of key cell identity genes uncovers determinants of ES cell identity and homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 111: E1581-90
Tajonar A, Maehr R, Hu G, et al. (2013) Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells. Stem Cells (Dayton, Ohio). 31: 2833-41
Aceto N, Sausgruber N, Brinkhaus H, et al. (2012) Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop Nature Medicine. 18: 529-537
Sun T, Aceto N, Meerbrey KL, et al. (2011) Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase. Cell. 144: 703-18
Meerbrey KL, Hu G, Kessler JD, et al. (2011) The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 3665-70
Hu G, Kim J, Xu Q, et al. (2009) A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal Genes and Development. 23: 837-848
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