Julian J. Raffoul, Ph.D.
Affiliations: | 2004 | Wayne State University, Detroit, MI, United States |
Area:
Nutrition, Molecular BiologyGoogle:
"Julian Raffoul"Parents
Sign in to add mentor| Ahmad R. Heydari | grad student | 2004 | Wayne State | |
| (Characterization of an apurinic /apyrimidinic endonuclease heterozygous knockout mouse: Identifying nutrient-gene and gene-environment interactions on DNA repair.) | ||||
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Publications
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| Raffoul JJ, Heydari AR, Hillman GG. (2012) DNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary Agents. Journal of Oncology. 2012: 370481 |
| Unnikrishnan A, Raffoul JJ, Patel HV, et al. (2009) Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice. Free Radical Biology & Medicine. 46: 1488-99 |
| Raffoul JJ, Banerjee S, Singh-Gupta V, et al. (2007) Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo. Cancer Research. 67: 2141-9 |
| Cabelof DC, Raffoul JJ, Ge Y, et al. (2006) Age-related loss of the DNA repair response following exposure to oxidative stress. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 61: 427-34 |
| Cabelof DC, Raffoul JJ, Nakamura J, et al. (2004) Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency. The Journal of Biological Chemistry. 279: 36504-13 |
| Raffoul JJ, Cabelof DC, Nakamura J, et al. (2004) Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair. The Journal of Biological Chemistry. 279: 18425-33 |
| Cabelof DC, Guo Z, Raffoul JJ, et al. (2003) Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Cancer Research. 63: 5799-807 |
| Cabelof DC, Yanamadala S, Raffoul JJ, et al. (2003) Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline. Dna Repair. 2: 295-307 |
| Cabelof DC, Raffoul JJ, Yanamadala S, et al. (2002) Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo. Carcinogenesis. 23: 1419-25 |
| Cabelof DC, Raffoul JJ, Yanamadala S, et al. (2002) Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice. Mutation Research. 500: 135-45 |