George Angus McQuibban
Affiliations: | University of Toronto, Toronto, ON, Canada |
Area:
Mitochondria autophagy, rhomboid proteasesWebsite:
http://biochemistry.utoronto.ca/person/g-angus-mcquibban/Google:
"George McQuibban"Mean distance: 7.11 | S | N | B | C | P |
Parents
Sign in to add mentor| Peter N. Lewis | grad student | 1992-1995 | University of Toronto | |
| (Yeast nucleosome and chromatin assembly. PhD) | ||||
| Christopher M. Overall | grad student | 2001 | UBC (Cell Biology Tree) | |
| (Matrix metalloproteinase processing of monocyte chemokines.) | ||||
| Matthew Freeman | post-doc | (FlyTree) | ||
Children
Sign in to add trainee| Ryder Whittaker Hawkins | research assistant | 2014 | University of Toronto (Cell Biology Tree) |
| Jarungjit Rujiviphat | grad student | 2014 | University of Toronto (FlyTree) |
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Publications
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| Serricchio M, Vissa A, Kim PK, et al. (2018) Cardiolipin synthesizing enzymes form a complex that interacts with cardiolipin-dependent membrane organizing proteins. Biochimica Et Biophysica Acta |
| Shi G, McQuibban GA. (2017) The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism. Cell Reports. 18: 1458-1472 |
| Wang Y, Serricchio M, Jauregui M, et al. (2015) Deubiquitinating enzymes regulate PARK2-mediated mitophagy. Autophagy. 11: 595-606 |
| Rujiviphat J, Wong MK, Won A, et al. (2015) Mitochondrial Genome Maintenance 1 (Mgm1) Protein Alters Membrane Topology and Promotes Local Membrane Bending. Journal of Molecular Biology |
| Chan EY, McQuibban GA. (2013) The mitochondrial rhomboid protease: its rise from obscurity to the pinnacle of disease-relevant genes. Biochimica Et Biophysica Acta. 1828: 2916-25 |
| Rujiviphat J, Wong MK, Shih Y, et al. (2013) Mgm1 Alters Membrane Topology and Promotes Local Membrane Bending to Drive Mitochondrial Membrane Fusion Biophysical Journal. 104: 98a |
| Chan EY, McQuibban GA. (2012) Phosphatidylserine decarboxylase 1 (Psd1) promotes mitochondrial fusion by regulating the biophysical properties of the mitochondrial membrane and alternative topogenesis of mitochondrial genome maintenance protein 1 (Mgm1). The Journal of Biological Chemistry. 287: 40131-9 |
| Abutbul-Ionita I, Rujiviphat J, Nir I, et al. (2012) Membrane tethering and nucleotide-dependent conformational changes drive mitochondrial genome maintenance (Mgm1) protein-mediated membrane fusion. The Journal of Biological Chemistry. 287: 36634-8 |
| Wang Y, Nartiss Y, Steipe B, et al. (2012) ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy Autophagy. 8: 1462-1476 |
| Shanbhag R, Shi G, Rujiviphat J, et al. (2012) The emerging role of proteolysis in mitochondrial quality control and the etiology of Parkinson's disease. Parkinson's Disease. 2012: 382175 |