George Angus McQuibban

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Mitochondria autophagy, rhomboid proteases
Website:
http://biochemistry.utoronto.ca/person/g-angus-mcquibban/
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"George McQuibban"
Mean distance: 7.11
 
SNBCP

Parents

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Peter N. Lewis grad student 1992-1995 University of Toronto
 (PhD)
Christopher M. Overall grad student 2001 UBC (Cell Biology Tree)
 (Matrix metalloproteinase processing of monocyte chemokines.)
Matthew Freeman post-doc (FlyTree)
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Publications

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Wang Y, Serricchio M, Jauregui M, et al. (2015) Deubiquitinating enzymes regulate PARK2-mediated mitophagy. Autophagy. 11: 595-606
Rujiviphat J, Wong MK, Won A, et al. (2015) Mitochondrial Genome Maintenance 1 (Mgm1) Protein Alters Membrane Topology and Promotes Local Membrane Bending. Journal of Molecular Biology
Sing A, Tsatskis Y, Fabian L, et al. (2014) The atypical cadherin fat directly regulates mitochondrial function and metabolic state. Cell. 158: 1293-308
Abutbul-Ionita I, Rujiviphat J, Nir I, et al. (2012) Membrane tethering and nucleotide-dependent conformational changes drive mitochondrial genome maintenance (Mgm1) protein-mediated membrane fusion. The Journal of Biological Chemistry. 287: 36634-8
Shanbhag R, Shi G, Rujiviphat J, et al. (2012) The emerging role of proteolysis in mitochondrial quality control and the etiology of Parkinson's disease. Parkinson's Disease. 2012: 382175
Shi G, Lee JR, Grimes DA, et al. (2011) Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease. Human Molecular Genetics. 20: 1966-74
Rujiviphat J, Meglei G, Rubinstein JL, et al. (2009) Phospholipid association is essential for dynamin-related protein Mgm1 to function in mitochondrial membrane fusion. The Journal of Biological Chemistry. 284: 28682-6
Whitworth AJ, Lee JR, Ho VM, et al. (2008) Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin. Disease Models & Mechanisms. 1: 168-74; discussion 1
McQuibban GA, Lee JR, Zheng L, et al. (2006) Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function. Current Biology : Cb. 16: 982-9
Zhang K, McQuibban GA, Silva C, et al. (2003) HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration. Nature Neuroscience. 6: 1064-71
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