Achim Brinker

Affiliations: 
2003- Scripps Research Institute 
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"Achim Brinker"
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Publications

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Johnson SM, Sharif O, Mak PA, et al. (2014) A biochemical screen for GroEL/GroES inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 786-9
Ramadoss NS, Alumasa JN, Cheng L, et al. (2013) Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 10282-7
Staerk J, Lyssiotis CA, Medeiro LA, et al. (2011) Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. Angewandte Chemie (International Ed. in English). 50: 5734-6
Nam TG, Lee J, Walker JR, et al. (2011) Identification and characterization of small-molecule inducers of fetal hemoglobin. Chemmedchem. 6: 777-80
Crowther GJ, Napuli AJ, Gilligan JH, et al. (2011) Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds. Molecular and Biochemical Parasitology. 175: 21-9
O'Leary DA, Vargas L, Sharif O, et al. (2010) HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1. Current Chemical Genomics. 4: 9-18
O'Leary DA, Sharif O, Anderson P, et al. (2009) Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. Plos One. 4: e8348
Sharif O, Hu H, Klock H, et al. (2009) Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4. Analytical Biochemistry. 392: 162-8
Lyssiotis CA, Foreman RK, Staerk J, et al. (2009) Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America. 106: 8912-7
Engels IH, Daguia C, Huynh T, et al. (2009) A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity. Analytical Biochemistry. 390: 85-7
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