Scott Younger

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2007-2012 Broad Institute, Cambridge, MA, United States 
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"Scott Younger"
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Malone CF, Dharia NV, Kugener G, et al. (2019) Abstract 2878: CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target inMYCN-amplified neuroblastoma Cancer Research
Shechner DM, Hacisuleyman E, Younger ST, et al. (2015) Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display. Nature Methods. 12: 664-70
Younger ST, Kenzelmann-Broz D, Jung H, et al. (2015) Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Research. 43: 4447-62
Younger ST, Corey DR. (2015) Identification and validation of miRNA target sites within nontraditional miRNA targets. Methods in Molecular Biology (Clifton, N.J.). 1206: 53-67
Younger ST, Rinn JL. (2014) 'Lnc'-ing enhancers to MYC regulation. Cell Research. 24: 643-4
Younger ST, Corey DR. (2011) Transcriptional regulation by miRNA mimics that target sequences downstream of gene termini. Molecular Biosystems. 7: 2383-8
Younger ST, Corey DR. (2011) Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters. Nucleic Acids Research. 39: 5682-91
Chu Y, Yue X, Younger ST, et al. (2010) Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter. Nucleic Acids Research. 38: 7736-48
Yue X, Schwartz JC, Chu Y, et al. (2010) Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini. Nature Chemical Biology. 6: 621-9
Younger ST, Pertsemlidis A, Corey DR. (2009) Predicting potential miRNA target sites within gene promoters. Bioorganic & Medicinal Chemistry Letters. 19: 3791-4
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