Jacob Schwartz

2005-2010 Biochemistry Univ. of Arizona, Tucson, AZ, United States 
"Jacob Schwartz"
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Wang X, Schwartz JC, Cech TR. (2015) Nucleic acid-binding specificity of human FUS protein. Nucleic Acids Research. 43: 7535-43
Schwartz JC, Cech TR, Parker RR. (2015) Biochemical Properties and Biological Functions of FET Proteins. Annual Review of Biochemistry. 84: 355-79
Schwartz JC, Podell ER, Han SS, et al. (2014) FUS is sequestered in nuclear aggregates in ALS patient fibroblasts. Molecular Biology of the Cell. 25: 2571-8
Schwartz JC, Wang X, Podell ER, et al. (2013) RNA seeds higher-order assembly of FUS protein. Cell Reports. 5: 918-25
Schwartz JC, Ebmeier CC, Podell ER, et al. (2012) FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. Genes & Development. 26: 2690-5
Peña-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, et al. (2011) Regulation of TFEB and V-ATPases by mTORC1. The Embo Journal. 30: 3242-58
Schwartz JC, Corey DR. (2011) Practical considerations for analyzing antigene RNAs (agRNAs): RNA immunoprecipitation of argonaute protein. Methods in Molecular Biology (Clifton, N.J.). 764: 301-15
Yue X, Schwartz JC, Chu Y, et al. (2010) Transcriptional regulation by small RNAs at sequences downstream from 3' gene termini. Nature Chemical Biology. 6: 621-9
Hu J, Matsui M, Gagnon KT, et al. (2009) Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs. Nature Biotechnology. 27: 478-84
Schwartz JC, Younger ST, Nguyen NB, et al. (2008) Antisense transcripts are targets for activating small RNAs. Nature Structural & Molecular Biology. 15: 842-8
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