Sean B. Joseph

Genomics Institute of the Novartis Research Foundation 
Drug Discovery and Development
"Sean Joseph"
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Daniela Bumbaca grad student 2013-2016 Genentech, Inc.
Scott McDonnel research scientist 2012-2013 Pfizer Global Research & Development
Charles A. Boswell research scientist 2013-2016 Genentech, Inc.
Susan Crowell research scientist 2014-2016 Genentech, Inc.
Jitendra Shrawan Kanodia research scientist 2014-2016 Genentech, Inc.
Danielle N. Mandikian research scientist 2014-2016 Genentech, Inc. (Neurotree)
Ben Shen research scientist 2014-2016 Genentech, Inc.
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Grzelak EM, Elshan NGRD, Shao S, et al. (2023) Pharmacological YAP activation promotes regenerative repair of cutaneous wounds. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305085120
Lee SC, Ma JSY, Kim MS, et al. (2021) A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand. Science Advances. 7
Bakowski MA, Beutler N, Wolff KC, et al. (2021) Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Nature Communications. 12: 3309
Lear S, Pflimlin E, Zhou Z, et al. (2020) Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity. Journal of Medicinal Chemistry
Chin EN, Yu C, Vartabedian VF, et al. (2020) Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.). 369: 993-999
Ardestani A, Li S, Annamalai K, et al. (2019) Neratinib protects pancreatic beta cells in diabetes. Nature Communications. 10: 5015
Bakowski MA, Shiroodi RK, Liu R, et al. (2019) Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections. Science Translational Medicine. 11
Mandikian D, Figueroa I, Oldendorp A, et al. (2018) Tissue Physiology of Cynomolgus Monkeys: Cross-Species Comparison and Implications for Translational Pharmacology. The Aaps Journal. 20: 107
Janes J, Young ME, Chen E, et al. (2018) The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. 115: 10750-10755
Mandikian D, Takahashi N, Lo AA, et al. (2018) Relative Target Affinities of T Cell-Dependent Bispecific Antibodies Determine Biodistribution in a Solid Tumor Mouse Model. Molecular Cancer Therapeutics
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