Ben Shen

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2014-2016 PTPK Genentech, Inc., San Francisco, CA, United States 
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"Ben Shen"
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Meng S, Steele AD, Yan W, et al. (2021) Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase. Nature Communications. 12: 5672
Annaval T, Teijaro CN, Adhikari A, et al. (2021) Cytochrome P450 Hydroxylase TnmL Catalyzing Sequential Hydroxylation with an Additional Proofreading Activity in Tiancimycin Biosynthesis. Acs Chemical Biology
Luo J, Yang D, Hindra, et al. (2021) Discovery of ammosesters by mining the Streptomyces uncialis DCA2648 genome revealing new insight into ammosamide biosynthesis. Journal of Industrial Microbiology & Biotechnology
Shen B, Tang Y, Baltz RH, et al. (2021) Introduction to the special issue: "Natural Product Discovery and Development in the Genomic Era: 2021". Journal of Industrial Microbiology & Biotechnology
Hindra H, Yang D, Luo J, et al. (2021) Submerged fermentation of Streptomyces uncialis providing a biotechnology platform for uncialamycin biosynthesis, engineering, and production. Journal of Industrial Microbiology & Biotechnology
Li Y, Weng X, Deng Y, et al. (2021) Semisynthesis and Biological Evaluation of Platencin Thioether Derivatives: Dual FabF and FabH Inhibitors against MRSA. Acs Medicinal Chemistry Letters. 12: 433-442
Adhikari A, Shen B, Rader C. (2021) Challenges and Opportunities to Develop Enediyne Natural Products as Payloads for Antibody-Drug Conjugates. Antibody Therapeutics. 4: 1-15
Cao M, Zheng C, Yang D, et al. (2021) Cryptic sulfur incorporation in thioangucycline biosynthesis. Angewandte Chemie (International Ed. in English)
Zheng CJ, Kalkreuter E, Fan BY, et al. (2020) PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine -Acetyltransferases. Acs Chemical Biology
Lohman JR, Shen B. (2020) The LnmK Bifunctional Acyltransferase/Decarboxylase Specifying (2)-Methylmalonyl-CoA and Employing Substrate-Assisted Catalysis for Polyketide Biosynthesis. Biochemistry
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