Irene Saugar

Affiliations: 
University of Madrid, Spain 
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"Irene Saugar"
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Lehmann CP, Saugar I, Tercero JA. (2021) Fluorescence Microscopy for Analysis of Relocalization of Structure-Specific Endonucleases. Methods in Molecular Biology (Clifton, N.J.). 2153: 521-534
Waizenegger A, Urulangodi M, Lehmann CP, et al. (2020) Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity. Nature Communications. 11: 5746
Jiménez-Martín A, Saugar I, Joseph CR, et al. (2020) The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks. Science Advances. 6: eaaz3327
Saugar I, Jiménez-Martín A, Tercero JA. (2017) Subnuclear Relocalization of Structure-Specific Endonucleases in Response to DNA Damage. Cell Reports. 20: 1553-1562
Ortiz-Bazán MÁ, Gallo-Fernández M, Saugar I, et al. (2014) Rad5 plays a major role in the cellular response to DNA damage during chromosome replication. Cell Reports. 9: 460-8
Saugar I, Ortiz-Bazán MÁ, Tercero JA. (2014) Tolerating DNA damage during eukaryotic chromosome replication. Experimental Cell Research. 329: 170-7
Saugar I, Vázquez MV, Gallo-Fernández M, et al. (2013) Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage. Nucleic Acids Research. 41: 8943-58
Gallo-Fernández M, Saugar I, Ortiz-Bazán MÁ, et al. (2012) Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4. Nucleic Acids Research. 40: 8325-35
Saugar I, Parker JL, Zhao S, et al. (2012) The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA. Nucleic Acids Research. 40: 245-57
Brückner S, Kern S, Birke R, et al. (2011) The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development. Genetics. 189: 479-94
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